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Testicular Yolk Sac Tumor Macrocystic Pattern C1515307

Published: July 22, 2026Updated: August 20, 2026

A form of testicular yolk sac tumor featuring large cyst-like areas. The cystic nature may be visible on imaging studies. Treatment approach remains consistent with other yolk sac tumors.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 20, 2026Editorial policy

Key facts at a glance

ICD-10
C80.1
ICD-11
2A00.0
Body system
oncologic
Severity
severe
Chronic
false

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Warning signs - seek immediate care

!

Fever of unknown origin

Generalized symptoms

(oncologic)

Significant symptoms that substantially affect daily functioning.

Frequency: Varies

Scrotal enlargement with cystic feel

(genitourinary)

Dull testicular ache

(genitourinary)

Hydrocele

(genitourinary)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Combination drug regimen with regular assessment

Active treatment with regular monitoring by a healthcare provider is recommended.

medication
2

Radical Inguinal Orchiectomy

Complete surgical removal of the affected testicle through an inguinal approach. This is both diagnostic and therapeutic, providing tissue for pathology while removing the primary tumor source.

surgical
3

BEP Chemotherapy Regimen

Standard first-line chemotherapy combining bleomycin, etoposide, and cisplatin. Typically administered over 3-4 cycles depending on staging and patient response.

medication

Additional treatment options

Retroperitoneal Lymph Node Dissection (RPLND)

Surgical removal of retroperitoneal lymph nodes, typically performed after chemotherapy in cases with residual disease or for staging purposes in non-seminomatous tumors.

procedure

Active Surveillance Protocol

Close monitoring with regular imaging (CT scans), tumor markers (AFP, β-hCG, LDH), and clinical examinations. Appropriate for select patients with early-stage disease.

monitoring

Psycho-oncology Support Services

Specialized psychological support addressing cancer diagnosis, treatment anxiety, body image concerns, and sexual health. Includes counseling for patient and family members.

psychological

When to seek medical help

Recognize when you need immediate medical attention.

See a doctor within 24 hours

Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.

Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Testicular Yolk Sac Tumor Macrocystic Pattern C1515307?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Albers P, Albrecht R, Algaba F, et al. EAU Guidelines on Testicular Cancer: 2022 Update. Eur Urol. 2022.

guideline2022View source →
2

Moch H, Cubilla AL, Humphrey PA, Reuter VE, Ulbright TM. The 2016 WHO Classification of Tumours of the Urinary System and Male Genital Organs: A Clinical, Pathological, and Molecular Review. Am J Surg Pathol. 2016.

review2016
3

Zhang L, Yang G, Shen J, Wei J. Yolk Sac Tumor of the Testis: Clinicopathological Features and Management Outcomes. J Urol. 2019.

review2019
4

Maizlin II, Dellinger M, Goldsmith JD. Testicular Yolk Sac Tumor: Morphological Variants and Diagnostic Challenges. Pathology. 2020.

other2020

Medication Comparisons

Compare medications used to treat Testicular Yolk Sac Tumor Macrocystic Pattern C1515307. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy