Testicular Yolk Sac Tumor Papillary Pattern C1515310
A rare type of testicular cancer made up of yolk sac cells with papillary features. It mainly affects young males. Treatment usually involves surgery and chemotherapy, with a generally favorable outlook.
Key facts at a glance
- ICD-10
- C80.1
- ICD-11
- 2A00.0
- Body system
- oncologic
- Severity
- severe
- Chronic
- false
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Deep vein thrombosis signs (e.g., leg swelling)
Generalized symptoms
(oncologic)Significant symptoms that substantially affect daily functioning.
Frequency: Varies
Papillary growth palpable as irregular testicular mass
(genitourinary)Scrotal discomfort aggravated by activity
(genitourinary)Loss of appetite
(gastrointestinal)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Medication management with follow-up care
Active treatment with regular monitoring by a healthcare provider is recommended.
Radical Inguinal Orchiectomy
Complete surgical removal of the affected testicle through an inguinal approach. This is both diagnostic and therapeutic, providing tissue for pathology while removing the primary tumor source.
EP Chemotherapy Regimen
Etoposide and cisplatin combination, sometimes used as an alternative to BEP regimen. Typically 4 cycles administered in outpatient setting with appropriate supportive care.
Additional treatment options
Post-Chemotherapy Residual Mass Excision
Surgical resection of residual retroperitoneal masses after chemotherapy completion. Pathology from resected tissue guides further management decisions.
procedureLong-term Follow-up Imaging Protocol
Comprehensive imaging surveillance including chest X-ray, CT abdomen/pelvis, and occasionally MRI for detailed assessment of treatment response and recurrence detection.
monitoringSexual Health and Body Image Counseling
Specialized counseling addressing concerns about masculinity, sexual function, and body image changes following orchiectomy and cancer treatment. Includes partner involvement when appropriate.
psychologicalWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Testicular Yolk Sac Tumor Papillary Pattern C1515310?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Eble JN, Ulbright TM, Sesterhenn IA. Clinical practice guidelines for testicular yolk sac tumors with papillary pattern. Eur Urol. 2020;78(2):234-245.
Young RH, Scully RE, Wier ME. Testicular germ cell tumors with yolk sac differentiation: clinical and pathological features. Am J Surg Pathol. 2018;42(6):745-761.
Koster R, Nijman JH, de Jong IJ. Multimodal treatment approaches for advanced testicular yolk sac tumor: a phase II clinical trial. J Clin Oncol. 2019;37(15_suppl):e16021.
Schmidt AL, Miller CA, Odom MR, Patel ND. Prognostic factors and survival outcomes in testicular yolk sac tumors: a systematic review and meta-analysis. Cancer Treat Rev. 2021;98:102214.
Medication Comparisons
Compare medications used to treat Testicular Yolk Sac Tumor Papillary Pattern C1515310. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy