Thrombophilia Due To Activated Protein C Resistance C1861171
A hereditary condition where blood fails to properly break down a clotting protein, increasing clot formation risk. It affects both males and females and is often managed with blood-thinning medications.
Key facts at a glance
- ICD-10
- D68.51
- ICD-11
- 3A00.0
- Body system
- hematologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Pulmonary embolism
Cerebral venous thrombosis
Deep vein thrombosis
(cardiovascular)Generalized symptoms
(hematologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Superficial thrombophlebitis
(cardiovascular)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Anticoagulation therapy
Long-term anticoagulant medication to prevent abnormal blood clot formation. Typically involves regular monitoring of clotting parameters and dose adjustments as needed.
Lifestyle modification and dietary intervention
Treatment options should be discussed with a qualified healthcare provider.
Physical activity and mobility
Regular low-impact exercise such as walking or swimming combined with avoiding prolonged immobility to promote healthy blood circulation and reduce clot risk.
Additional treatment options
Regular thrombophilia monitoring
Periodic blood tests to monitor clotting factors and treatment efficacy, including checking for new symptoms of clotting or bleeding complications.
monitoringBalanced nutrition for vascular health
Diet rich in fruits, vegetables, and omega-3 fatty acids while maintaining healthy weight. Adequate hydration is essential for optimal blood viscosity.
dietaryCompression therapy
Graduated compression stockings may be recommended to improve venous return and reduce swelling in patients with associated venous insufficiency.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Thrombophilia Due To Activated Protein C Resistance C1861171?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Stevens SM, Woller SC, Bauer KA, et al. Guidance for the evaluation and treatment of hereditary and acquired thrombophilia. J Thromb Thrombolysis. 2016.
Orlando C, Boudes E, Rugeri L. Activated protein C resistance: Molecular mechanisms and clinical implications. Haemophilia. 2018.
Simioni P, Tormene D, Prandoni P, et al. Factor V Leiden and the risk of venous thrombosis: A meta-analysis of individual data. Blood. 2019.
Middeldorp S, van Hylckama Vlieg A. Does thrombophilia testing help in the clinical management of patients? Br J Haematol. 2018.
Medication Comparisons
Compare medications used to treat Thrombophilia Due To Activated Protein C Resistance C1861171. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy