Tpm3 Related Myopathy Cn323193
A genetic muscle disease causing weakness and developmental delays. Physical therapy and supportive care help manage symptoms and improve function.
Key facts at a glance
- ICD-10
- Q79.9
- ICD-11
- LA00.0
- Body system
- musculoskeletal
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Respiratory compromise
Distal muscle weakness
(musculoskeletal)Joint pain or stiffness
(musculoskeletal)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Scoliosis
(musculoskeletal)Exercise intolerance
(musculoskeletal)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Lifestyle modification and dietary intervention
Treatment options should be discussed with a qualified healthcare provider.
Motor Development and Gross Motor Skill Training
Structured PT program emphasizing functional movements, balance training, and gradual strength building tailored to individual capabilities.
Serial Musculoskeletal Assessments
Regular orthopedic evaluations to detect and manage scoliosis, hip dysplasia, and contractures that commonly develop in congenital myopathies.
Additional treatment options
Home Exercise Program Implementation
Daily prescribed exercises to maintain range of motion and strength, integrated into family routines for consistency.
lifestyleAnti-inflammatory Dietary Pattern
Mediterranean-style diet rich in omega-3 fatty acids, antioxidants, and fresh produce to potentially reduce muscle inflammation.
dietaryPsychosocial Support and Counseling
Mental health support addressing body image concerns, social challenges, and emotional adjustment to living with a chronic condition.
psychologicalWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Tpm3 Related Myopathy Cn323193?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Clarke NF, North KN. Congenital myopathies related to tropomyosin. Neuromuscul Disord. 2020.
Wang CH, et al. Consensus statement on standard of care for congenital muscle diseases. J Child Neurol. 2019.
Lawlor MW, et al. Novel TPM3 mutation causing cap myopathy: phenotypic and molecular characterization. Muscle Nerve. 2018.
Malfatti E, et al. Muscle pathology spectrum in TPM3-related myopathies: a systematic review. Neurology. 2022.
Medication Comparisons
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View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy