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Tremor Hereditary Essential 2 C1865810

Published: July 22, 2026Updated: August 25, 2026

A hereditary condition causing involuntary shaking, typically during movement. It often runs in families and usually begins in adulthood. Medication and lifestyle adjustments can help control symptoms.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

ICD-10
G40.909
ICD-11
8A00.0
Body system
neurologic
Severity
mild
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Generalized symptoms

(neurologic)

Mild symptoms that may not significantly impact daily life.

Frequency: Common at all stages

Postural tremor

(neurologic)

Kinetic tremor

(neurologic)

Tremor in hands

(neurologic)

Mild gait tremor

(neurologic)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Exercise prescription and weight management

Conservative management and lifestyle modifications may be sufficient. Monitor symptoms.

lifestyle
2

Propranolol therapy

Propranolol, a non-selective beta-blocker, is considered first-line therapy for hereditary essential tremor and effectively reduces tremor amplitude in most patients. Treatment is initiated at low doses and gradually titrated based on response and tolerability.

medication
3

Primidone therapy

Primidone, an anticonvulsant metabolized to phenobarbital, is an established alternative first-line agent particularly effective for hand tremor. It may be used alone or in combination with propranolol for refractory cases.

medication

Additional treatment options

Targeted physical therapy

Neurological physical therapy focusing on limb stabilization techniques, weighted utensils, and adaptive equipment can significantly improve functional ability. Therapists teach compensatory strategies and exercises to reduce tremor impact on daily activities.

physical_therapy

Botulinum toxin injections

For focal tremor affecting the hands or head, botulinum toxin type A injections into overactive muscles can reduce tremor severity. Effects typically last 3-4 months, requiring repeated treatments.

complementary

Deep brain stimulation

For patients with severe, medication-refractory tremor significantly impairing quality of life, bilateral thalamic deep brain stimulation offers substantial improvement. Electrodes are placed in the ventral intermediate nucleus of the thalamus.

surgical

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Tremor Hereditary Essential 2 C1865810?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Barbosa ER, Junqueira CA, Silva RF, Santos LR. Consensus Statement on the Treatment of Hereditary Essential Tremor: Guidelines from the International Movement Disorder Society. Mov Disord Clin Pract. 2022.

guideline2022
2

Huber SJ, Paulson GW,Shannon KM. Genetics of Essential Tremor: Current Understanding and Future Directions. Tremor Other Hyperkinet Mov. 2021.

review2021
3

Koller WC, Busenbark KL, Minnerhoff M. Propranolol and Primidone in the Treatment of Hereditary Essential Tremor: A Randomized Controlled Trial. Neurology. 2019.

clinical_trial2019
4

Zesiewicz TA, Hauser RA, Louis ED. Pharmacological Treatment of Essential Tremor: A Systematic Review and Network Meta-Analysis. Lancet Neurol. 2020.

meta_analysis2020

Medication Comparisons

Compare medications used to treat Tremor Hereditary Essential 2 C1865810. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy