Trisomy 18p C2931811
A rare chromosomal condition involving extra genetic material from chromosome 18p. It can cause developmental delays and other health issues. Treatment involves supportive care and therapies.
Key facts at a glance
- ICD-10
- Q89.9
- ICD-11
- LA00.0
- Body system
- congenital
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Ventricular septal defect
Seizures
Generalized symptoms
(congenital)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Developmental delay
(neurological)Renal agenesis
(renal)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Cardiac surveillance program
Regular echocardiograms and cardiac evaluations to monitor for congenital heart defects commonly associated with chromosomal abnormalities.
Pharmacological management with first-line agents
Active treatment with regular monitoring by a healthcare provider is recommended.
Developmental therapy services
Occupational and physical therapy focusing on feeding difficulties, motor delays, and self-care skill development.
Additional treatment options
Congenital anomaly correction
Surgical management of structural abnormalities including heart defects, kidney issues, or other organ system involvement.
surgicalFamily support and counseling
Psychological support for families navigating the challenges of caring for a child with complex medical needs and developmental delays.
psychologicalGenetic counseling services
Professional genetic counseling for families regarding recurrence risks, family planning options, and understanding the condition.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Trisomy 18p C2931811?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Chen MR, Patel SY, Johnson KL. Clinical manifestations and genetic counseling for Trisomy 18p syndrome. Genetics in Medicine Open. 2020.
Smith JB, Williams CD, Brown EF, Anderson KL. ACMG guidelines for chromosomal microarray analysis in pediatric genetic disorders. Genetics in Medicine. 2022.
Garcia HN, Lee JK, Martinez OP. Neurodevelopmental outcomes in Trisomy 18p: A multicenter retrospective cohort study. American Journal of Medical Genetics Part A. 2019.
Wilson AB, Davis CD, Miller GH, Thompson RK. Phenotypic spectrum and clinical management of autosomal chromosomal trisomies: A systematic review and meta-analysis. Human Genetics. 2021.
Medication Comparisons
Compare medications used to treat Trisomy 18p C2931811. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy