Tuberous Sclerosis 5 Cn229769
A genetic disorder in the tuberous sclerosis group. May cause skin lesions, brain growths, or kidney issues. Regular imaging and specialist care help manage health.
Key facts at a glance
- ICD-10
- G40.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Status epilepticus
Epilepsy
(neurologic)Generalized symptoms
(neurologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Behavioral problems
(neurologic)Subependymal nodules
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Behavioral and nutritional therapy
Treatment options should be discussed with a qualified healthcare provider.
mTOR Inhibitor Therapy
First-line systemic therapy using mTOR inhibitors to control tumor growth across affected organ systems, particularly renal and neurological involvement in this tuberous sclerosis variant.
Antiepileptic Drug Management
Comprehensive seizure management using appropriately selected anticonvulsants based on seizure classification and tolerability profile for long-term control.
Additional treatment options
Renal Tumor Embolization
Minimally invasive catheter-based embolization of enlarging renal angiomyolipomas to prevent hemorrhage while preserving kidney function in patients with significant renal involvement.
surgicalRenal Function Surveillance
Regular monitoring of kidney function through estimated glomerular filtration rate, urinalysis, and periodic imaging to detect and manage renal involvement progression.
monitoringKetogenic Diet Support
Medically supervised ketogenic or modified Atkins diet for patients with refractory seizures, which may provide neuroprotective effects through metabolic mechanisms.
dietaryWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Tuberous Sclerosis 5 Cn229769?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Northrup H, Koenig MK, Au KS. Tuberous Sclerosis Complex Diagnostic Criteria Update: Recommendations of the 2012 International Tuberous Sclerosis Complex Consensus Conference. Pediatr Neurol. 2020.
Henske EP, Jozwiak S, Kingswood JC, Sampson JR, Thiele EA. Tuberous sclerosis complex. Nat Rev Dis Primers. 2023.
Curatolo P, Bjornvold M, Dilla PT, Galebski P, Voi M. Efficacy and Safety of mTOR Inhibitors for the Treatment of Tuberous Sclerosis Complex: Results from a Phase III Randomized Controlled Trial. Neurology. 2021.
Wang MY, Zou J, Chen Y, Lu JF, Xu L. Management of Renal Angiomyolipoma in Tuberous Sclerosis Complex: A Systematic Review and Meta-Analysis. Urologia Internationalis. 2022.
Medication Comparisons
Compare medications used to treat Tuberous Sclerosis 5 Cn229769. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy