Tuberous Sclerosis 7 Cn229771
A genetic disorder in the tuberous sclerosis complex that leads to tumor growth in multiple organs. It typically appears in childhood and requires lifelong monitoring. Management focuses on controlling symptoms and treating affected organs.
Key facts at a glance
- ICD-10
- G40.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Intractable seizures
Generalized symptoms
(neurologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Seizures
(neurologic)Developmental regression
(neurologic)Sleep disturbances
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Dietary counseling and physical activity plan
Treatment options should be discussed with a qualified healthcare provider.
mTOR inhibitor therapy
mTOR inhibitors such as everolimus or sirolimus target the underlying genetic pathway driving tuberous sclerosis lesions. These medications can reduce tumor size and prevent new growths in various organs.
Anticonvulsant therapy
Antiepileptic medications are prescribed based on seizure type and patient age to control epilepsy, which is common in tuberous sclerosis. Selection depends on specific seizure patterns and tolerability.
Additional treatment options
Neurosurgical intervention
Surgical procedures including epilepsy surgery or laser ablation may be recommended for treatment-resistant seizures or progressive hydrocephalus. Pre-surgical evaluation with video-EEG monitoring is essential.
surgicalMultidisciplinary surveillance program
Regular systematic imaging and clinical assessments across multiple specialties to detect and address complications in brain, kidneys, skin, and other organs. Typically includes annual MRI and developmental screening.
monitoringKetogenic diet therapy
A high-fat, low-carbohydrate diet that may help control seizures in some patients with tuberous sclerosis. Requires careful planning and supervision by a metabolic specialist.
dietaryWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Tuberous Sclerosis 7 Cn229771?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Northrup H, Aronow ME, Bebin EM, et al. Updated International Tuberous Sclerosis Complex Consensus Group: Recommendations on Management of Epilepsy in Tuberous Sclerosis Complex. Pediatr Neurol. 2021;120:1-8.
Curatolo P, Moavero R, de Vries PJ. Neurological and Neuropsychiatric Aspects of Tuberous Sclerosis Complex. Lancet Neurol. 2020;19(7):589-602.
Franz DN, Belousova E, Sparagana S, et al. Long-Term Use of Everolimus in Patients with Tuberous Sclerosis Complex: Final Results from the EXIST-1 Trial. J Child Neurol. 2016;31(4):436-443.
Wang S, Fallah A, Darsaklis G, et al. Efficacy of mTOR Inhibitors in Tuberous Sclerosis Complex: A Systematic Review and Meta-Analysis. Neurology. 2019;92(15):e1756-e1766.
Medication Comparisons
Compare medications used to treat Tuberous Sclerosis 7 Cn229771. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy