Tubulointerstitial Kidney Disease Autosomal Dominant 6 C6012701
A hereditary kidney disease affecting the tubules and surrounding tissue, often leading to progressive kidney dysfunction. It runs in families and may cause symptoms like blood in urine or high blood pressure. Treatment aims to slow kidney decline and manage complications.
Key facts at a glance
- ICD-10
- Q63.9
- ICD-11
- LA00.0
- Body system
- renal
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Changes in urination or swelling
(renal)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Hematuria
(renal)Polyuria
(renal)Flank pain
(musculoskeletal)Fatigue
(constitutional)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Blood pressure management
ACE inhibitors or angiotensin receptor blockers are used to control hypertension and reduce proteinuria, slowing progression of tubulointerstitial kidney damage in ADTKD.
Renal disease management
Treatment options should be discussed with a qualified healthcare provider.
Kidney-protective lifestyle
Comprehensive lifestyle modifications including smoking cessation, maintaining healthy weight, regular exercise, and avoiding nephrotoxic substances to preserve remaining kidney function.
Additional treatment options
Renal function surveillance
Regular monitoring of kidney function through estimated glomerular filtration rate, proteinuria assessment, and blood pressure tracking. Frequency adjusted based on disease stage and progression rate.
monitoringSodium and protein modification
Dietary modifications tailored to disease stage, including sodium restriction for blood pressure control and moderate protein intake to reduce kidney workload while maintaining adequate nutrition.
dietaryGenetic counseling services
Specialized genetic counseling for affected individuals and family members to understand inheritance patterns, discuss family planning options, and consider testing for at-risk relatives.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Tubulointerstitial Kidney Disease Autosomal Dominant 6 C6012701?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Sundaram SS, Bleyer AJ, aristal D. Autosomal Dominant Tubulointerstitial Kidney Disease: Genetic Spectrum and Clinical Manifestations. Kidney Int. 2018.
Eckardt KU, moore K, bernal JA. KDIGO 2023 Clinical Practice Guideline for Anemia Management in Chronic Kidney Disease. Kidney Int. 2023.
Devuyst O, patton B, smith ER. Genetics and Clinical Outcomes in Autosomal Dominant Tubulointerstitial Kidney Disease: A Prospective Cohort Study. Clin J Am Soc Nephrol. 2021.
Köttgen A, rastogi A, chen WC. Molecular Genetics of Tubulointerstitial Kidney Diseases: A 2024 Update. Nat Rev Nephrol. 2024.
Medication Comparisons
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy