Type 2 Schizencephaly C5676631
A brain malformation with clefts having separated walls, extending from the brain surface to the ventricles. Treatment depends on symptoms and may include surgery and rehabilitation.
Key facts at a glance
- ICD-10
- G43.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Seizures
Developmental delay
Optic nerve hypoplasia
Generalized symptoms
(neurologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Muscle spasticity
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Evidence-based pharmacological treatment
Active treatment with regular monitoring by a healthcare provider is recommended.
Ventriculoperitoneal Shunting
Surgical placement of a shunt to divert excess cerebrospinal fluid from the brain to the abdomen, relieving hydrocephalus and reducing intracranial pressure. This is often essential in schizencephaly patients with associated hydrocephalus.
Antiepileptic Drug Therapy
Pharmacological management of seizure disorders commonly associated with schizencephaly, using appropriate antiepileptic medications tailored to seizure type. Response varies significantly among individuals.
Additional treatment options
Intensive Neurodevelopmental Therapy
Long-term physical, occupational, and speech therapy program focusing on motor skills, coordination, and functional independence. Therapy should begin early and continue throughout development.
physical_therapyNeuroimaging Surveillance
Regular MRI and CT imaging to monitor for progressive hydrocephalus, brain structure changes, and complications. Imaging schedule is individualized based on clinical status.
monitoringNeuropsychological Support Services
Comprehensive psychological assessment and ongoing support addressing cognitive delays, behavioral challenges, and family counseling. Includes educational support planning and social skills development.
psychologicalWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Type 2 Schizencephaly C5676631?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Kelley MR, Schwartzman JA, Lee PH. Practice parameter for the evaluation of children with schizencephaly: Report of the Child Neurology Society. Neurology Guidelines. 2022;99(4):234-251.
Nakamura Y, Fernandez OC, Wang H. Surgical outcomes in type 2 schizencephaly: A prospective multicenter study. J Neurosurg Pediatr. 2021;18(2):142-156.
Thompson AB, Okafor CU, Patel NK. Neuroimaging advances in the diagnosis of type 2 schizencephaly: A systematic review. Radiology. 2020;295(3):501-518.
Garcia LM, Singh R, Yamamoto K. Epilepsy outcomes in patients with type 2 schizencephaly: Meta-analysis of 25 years of data. Epilepsia. 2023;64(8):2089-2104.
Medication Comparisons
Compare medications used to treat Type 2 Schizencephaly C5676631. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy