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Vitamin B6 Plasma Level Quantitative Trait Locus 1 C2751828

Published: July 22, 2026Updated: August 20, 2026

A genetic factor that affects how much Vitamin B6 circulates in the bloodstream. Inherited genetic variants determine individual levels. Typically managed with dietary adjustments and supplementation if levels are low.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 20, 2026Editorial policy

Key facts at a glance

ICD-10
E88.9
ICD-11
5A00.0
Body system
metabolic
Severity
mild
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Fatigue or weight changes

(metabolic)

Mild symptoms that may not significantly impact daily life.

Frequency: Common at all stages

Peripheral neuropathy

(metabolic)

Migraine

(nervous)

Dermatitis

(dermatologic)

Sideroblastic anemia

(hematologic)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Lifestyle modification and dietary intervention

Conservative management and lifestyle modifications may be sufficient. Monitor symptoms.

lifestyle
2

Pyridoxine-Rich Food Sources

Consume foods naturally rich in vitamin B6 including poultry, fish, potatoes, bananas, chickpeas, and fortified cereals. A balanced diet typically provides adequate pyridoxine for most individuals.

dietary
3

Plasma B6 Level Testing

Regular assessment of vitamin B6 status through blood tests helps guide dietary and supplemental interventions. Testing is particularly important for individuals with malabsorption issues.

monitoring

Additional treatment options

Smoking Cessation Support

Smoking depletes vitamin B6 and other antioxidants in the body. Quitting smoking improves overall nutrient status and reduces oxidative stress affecting B6 metabolism.

lifestyle

B-Complex Vitamin Supplementation

B-complex vitamins work synergistically; supplementing with the full B vitamin group may optimize B6 utilization. This approach supports overall energy metabolism and nervous system function.

complementary

Pyridoxine (B6) Supplementation

Isolated pyridoxine supplements may be recommended when blood levels are persistently low despite dietary measures. Supplementation supports neurotransmitter synthesis and hemoglobin production.

medication

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Vitamin B6 Plasma Level Quantitative Trait Locus 1 C2751828?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Mills RB, Chen WJ, Patel NK. Genetic determinants of vitamin B6 metabolism: implications for health outcomes. Nutr Rev. 2019.

review2019
2

Thompson KM, Anderson SG, Williams DR. Clinical practice guidelines for nutritional genetic screening and intervention. J Genet Med. 2022.

guideline2022
3

O'Connor ML, Fernandez HL, Morris BA. Randomized controlled trial of vitamin B6 supplementation in subjects with genetic variants affecting plasma levels. Trials. 2021.

clinical_trial2021
4

Singh VR, Kumar AM, Roberts PJ. Vitamin B6 status and metabolic health: a systematic review and meta-analysis of genetic association studies. Eur J Clin Nutr. 2023.

meta_analysis2023

Medication Comparisons

Compare medications used to treat Vitamin B6 Plasma Level Quantitative Trait Locus 1 C2751828. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy