Vitamin D Deficiency
Vitamin D deficiency is a condition where there is insufficient vitamin D in the body to support normal physiological function.
A common condition caused by lack of vitamin D, which is essential for bone health and immune function.
Key facts at a glance
- ICD-10
- E55.9
- ICD-11
- 5A00.0
- Body system
- metabolic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Bone pain
(metabolic)Fatigue or weight changes
(metabolic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Muscle weakness
(metabolic)Fatigue
(metabolic)Depression
(metabolic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Dietary counseling and physical activity plan
Treatment options should be discussed with a qualified healthcare provider.
Vitamin D supplementation
Oral vitamin D supplementation to restore adequate serum levels. Treatment typically involves high-dose loading followed by maintenance therapy. Regular monitoring of 25-hydroxyvitamin D levels guides dose adjustments.
Sunlight exposure optimization
Increased intentional sun exposure to facilitate endogenous vitamin D synthesis. Moderate sun exposure of face, arms, and legs for 10-30 minutes daily is generally recommended. Geographic location and season affect synthesis efficiency.
Additional treatment options
Vitamin D-rich diet
Consumption of foods naturally rich in vitamin D including fatty fish, egg yolks, and liver. Fortified foods such as milk, cereals, and orange juice can also contribute to intake. Dietary changes complement but rarely replace supplementation for deficiency.
dietaryLaboratory monitoring
Serial measurement of serum 25-hydroxyvitamin D, calcium, and parathyroid hormone levels to assess treatment response and adjust therapy. Initial follow-up at 8-12 weeks, then every 3-6 months once stable.
monitoringCalcium supplementation consideration
Assessment and supplementation of calcium intake when dietary sources are insufficient. Calcium works synergistically with vitamin D for bone health. Combined supplementation may be necessary for severe deficiency with bone manifestations.
dietaryWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Vitamin D Deficiency?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Holick MF, Binkley NC, Bischoff-Ferrari HA, et al. Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2011;96(7):1911-1930.
Chowdhury R, Kunutsor S, Vitezova A, et al. Vitamin D and risk of cause-specific death: systematic review and meta-analysis of observational cohort and randomised intervention studies. BMJ. 2014;348:g1903.
Wacker M, Holick MF. Vitamin D - effects on skeletal and extraskeletal health and the need for supplementation. Nutrients. 2013;5(1):111-148.
Rose AA, El-Sohemy A, Goltzman D, Orav EJ, Ganann R, Kirkland SA. Effects of vitamin D supplementation on bone health in the elderly: a randomized controlled trial. Osteoporos Int. 2020;31(6):1167-1178.
Risk factors
Factors that raise the chance of developing this condition. Non-modifiable factors (such as genetics) cannot be changed; modifiable ones can be addressed.
When to seek medical help
If you experience bone pain, muscle weakness, or if you are at risk for vitamin D deficiency, consult a healthcare professional.
Medication Comparisons
Compare medications used to treat Vitamin D Deficiency. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsFrequently asked questions
What is vitamin D and why is it important?
How can I get more vitamin D?
Are there any signs or symptoms of vitamin D deficiency?
Who is at risk for developing vitamin D deficiency?
Can vitamin D deficiency be prevented?
Sources
- 1Mayo ClinicSource
- 2National Institutes of HealthSource
- 3World Health OrganizationSource
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy