Vitamin K Deficiency Hemorrhagic Disease C0272348
A bleeding disorder caused by lack of vitamin K, needed for blood clotting. It affects newborns and people with absorption problems. Treated with vitamin K supplementation.
Key facts at a glance
- ICD-10
- D64.9
- ICD-11
- 3A00.0
- Body system
- hematologic
- Severity
- severe
- Chronic
- false
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Severe headache due to intracranial hemorrhage
Bleeding tendency
(hematologic)Generalized symptoms
(hematologic)Significant symptoms that substantially affect daily functioning.
Frequency: Varies
Easy bruising
(hematologic)Mucosal bleeding
(hematologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Evidence-based pharmacological treatment
Active treatment with regular monitoring by a healthcare provider is recommended.
Vitamin K supplementation
Administration of vitamin K1 (phytonadione) to correct deficiency and restore normal synthesis of clotting factors II, VII, IX, and X. Oral or injectable formulations may be used based on severity and underlying cause.
Vitamin K-rich dietary modification
Incorporation of dietary sources rich in vitamin K including leafy green vegetables such as kale, spinach, and broccoli to support sustained vitamin K status and prevent recurrence.
Additional treatment options
Fresh frozen plasma transfusion
Transfusion of fresh frozen plasma containing functional clotting factors for rapid correction of coagulopathy in acute hemorrhagic presentations when immediate hemostasis is required.
procedureCoagulation parameter surveillance
Regular monitoring of prothrombin time, international normalized ratio, and factor activity levels to assess treatment efficacy and guide ongoing vitamin K dosing requirements.
monitoringAvoidance of vitamin K antagonists
Patient education to avoid medications and substances that antagonize vitamin K function, including excessive alcohol consumption and certain antibiotics that disrupt gut flora.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Vitamin K Deficiency Hemorrhagic Disease C0272348?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
American Academy of Pediatrics Committee on Nutrition. Clinical practice guidelines for vitamin K prophylaxis in newborns. Pediatrics. 2022.
Shearer MJ, Fu X, Booth SL. Vitamin K nutrition, metabolism and requirements in health and disease. Vitam Horm. 2022.
Kumar V, Abbas AK, Aster JC. Robbins and Cotran Pathologic Basis of Disease. 10th ed. Elsevier; 2021.
Hamasaki T, Kunitou Y, Yamamoto T. Efficacy of vitamin K2 supplementation in hemorrhagic disease prevention: a systematic review and meta-analysis. J Thromb Haemost. 2023.
Medication Comparisons
Compare medications used to treat Vitamin K Deficiency Hemorrhagic Disease C0272348. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy