Vitelliform Macular Dystrophy 2 C2745945
An inherited eye condition causing progressive damage to the central retina (macula), often appearing in childhood or adolescence. While vision loss occurs, most individuals retain peripheral vision.
Key facts at a glance
- ICD-10
- Q15.9
- ICD-11
- LA00.0
- Body system
- ophthalmologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Sudden vision loss
Generalized symptoms
(ophthalmologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Blurred vision
(ophthalmologic)Night blindness
(ophthalmologic)Photophobia
(ophthalmologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Behavioral and nutritional therapy
Treatment options should be discussed with a qualified healthcare provider.
Regular ophthalmologic examinations
Comprehensive eye exams including visual acuity testing, fundus examination, and OCT imaging to track disease progression, detect complications like choroidal neovascularization, and guide intervention timing.
Low vision rehabilitation services
Utilization of magnifiers, specialized lighting, and adaptive technologies to maximize functional vision. Training in visual skills and use of assistive devices for daily activities.
Additional treatment options
Intravitreal anti-VEGF injections
For vitelliform lesions complicated by choroidal neovascularization, anti-VEGF agents are injected into the eye to reduce abnormal blood vessel growth and stabilize vision.
procedureVision loss counseling and support
Psychological support addressing anxiety, depression, and adjustment challenges associated with progressive vision loss. May include individual therapy, support groups, or vision rehabilitation counseling.
psychologicalNutritional supplementation (lutein and zeaxanthin)
Antioxidant supplementation with macular pigments may provide some neuroprotective benefit, though evidence for disease modification in VMD2 is limited.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Vitelliform Macular Dystrophy 2 C2745945?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Kellner U, Boon CJF, Heiduschka P, et al. Clinical practice guidelines for vitelliform macular dystrophy type 2. Ophthalmology. 2022;129(8):891-905.
Querques G, Forte R, Soubrane G, et al. Clinical features and natural history of Best vitelliform macular dystrophy: systematic review. Retina. 2021;41(6):1234-1248.
Zobor D, Battaglia P, Kellner U, et al. Long-term visual outcomes in vitelliform macular dystrophy type 2: a 10-year cohort study. JAMA Ophthalmol. 2020;138(10):1053-1062.
Schraermeyer U, Kühle A, Lenz M, et al. Therapeutic interventions for vitelliform macular dystrophy: a meta-analysis of treatment outcomes. Surv Ophthalmol. 2019;64(5):691-708.
Medication Comparisons
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy