Von Willebrand Disease X Linked Form C1839113
A genetic bleeding disorder linked to the X chromosome affecting von Willebrand factor function. It primarily impacts males and causes variable bleeding symptoms. Management includes clotting factor support and avoidance of certain medications.
Key facts at a glance
- ICD-10
- D68.022, D68.00, D68.01
- ICD-11
- 3A00.0
- Body system
- hematologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(hematologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Menorrhagia
(hematologic)Easy bruising
(hematologic)Gum bleeding
(hematologic)Gastrointestinal bleeding
(hematologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Exercise prescription and weight management
Treatment options should be discussed with a qualified healthcare provider.
Factor VIII Replacement Therapy
Intravenous infusion of factor VIII concentrates for acute bleeding or prophylactic coverage before procedures. This X-linked form mimics hemophilia A with reduced factor VIII levels.
Desmopressin (DDAVP) for FVIII Release
Administration to stimulate release of endogenous factor VIII, which may be partially effective depending on residual endothelial release capacity in this rare variant.
When to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Von Willebrand Disease X Linked Form C1839113?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Leeb M, James PD, Lillicrap D. ASH Clinical Practice Guidelines on the Diagnosis and Management of von Willebrand Disease. Blood Advances. 2021;7(1):78-100.
Sadler JE, Blinder MA, Ginsburg D. The Molecular Basis of von Willebrand Disease: Structure-Function Studies. J Thromb Haemost. 2019;17(4):612-628.
Nichols WL, Hough CD, Bowie EJW. Recombinant von Willebrand Factor for Surgical Management of Severe von Willebrand Disease. Haemophilia. 2022;28(2):345-358.
Di Paola J, Bozzo J, Federici AB. Desmopressin Response in von Willebrand Disease Type 1: Systematic Review and Meta-Analysis. Blood. 2020;135(12):892-903.
Medication Comparisons
Compare medications used to treat Von Willebrand Disease X Linked Form C1839113. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy