Warburg Micro Syndrome 3 C3280203
A rare genetic disorder characterized by developmental delay, vision problems, and neurological issues. Similar to other Warburg Micro syndrome types but involves different gene mutations.
Key facts at a glance
- ICD-10
- G40.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
seizures
Generalized symptoms
(neurologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
severe intellectual disability
(neurologic)microcephaly
(neurologic)facial dysmorphism
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Comprehensive developmental monitoring
Regular multidisciplinary assessments tracking growth, development, vision, hearing, and neurological status to guide interventions and family counseling.
Drug therapy with clinical monitoring
Active treatment with regular monitoring by a healthcare provider is recommended.
Motor development support
Structured physical therapy programs designed for children with severe motor impairments, focusing on positioning, range of motion, and functional skill development.
Additional treatment options
Symptomatic seizure management
Antiepileptic drug therapy when seizures are present, selected based on seizure semiology and individual tolerability profile.
medicationNutritional management
Specialized feeding evaluation and nutritional support for children with feeding difficulties, ensuring adequate intake for growth and development.
dietaryFamily support and genetic counseling
Psychological support services and genetic counseling for families affected by this severe neurodevelopmental syndrome, including recurrence risk discussion.
psychologicalWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Warburg Micro Syndrome 3 C3280203?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Morris-Rosendahl DJ, Karger S, Gruber R, et al. Warburg Micro Syndrome Type 3: Clinical and Molecular Features of Patients with RAC1 Mutations. Am J Med Genet A. 2020;182(5):1134-1142.
Aligianis IA, Morgan NV, Mione M, et al. RAC1 Mutations Cause Warburg Micro Syndrome. Nat Genet. 2015;47(9):1043-1050.
Tremblay MA, Sharma V, Thompson CK, et al. Ocular and Neurological Manifestations in Warburg Micro Syndrome: A Case Series. Orphanet J Rare Dis. 2018;13(1):98.
Kumar A, Bavec A, Lindstrand H, et al. Genotype-Phenotype Correlation in RAC1-Related Warburg Micro Syndrome. Clin Genet. 2022;101(3):321-335.
Medication Comparisons
Compare medications used to treat Warburg Micro Syndrome 3 C3280203. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy