Wilms Tumor 1 Cn033288
A kidney cancer that primarily affects young children, often presenting as an abdominal mass. Treatment typically involves surgery, chemotherapy, and sometimes radiation.
Key facts at a glance
- ICD-10
- C80.1
- ICD-11
- 2A00.0
- Body system
- oncologic
- Severity
- severe
- Chronic
- false
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Hematuria
Hypertension
Abdominal mass
(abdominal)Generalized symptoms
(oncologic)Significant symptoms that substantially affect daily functioning.
Frequency: Varies
Abdominal pain
(abdominal)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Nephrectomy
Surgical removal of the affected kidney and tumor, which is the primary treatment for Wilms tumor. May be performed before or after chemotherapy depending on tumor stage.
Pharmacological management with first-line agents
Active treatment with regular monitoring by a healthcare provider is recommended.
Chemotherapy
Multi-agent chemotherapy regimens used before or after surgery to shrink tumors and eliminate microscopic disease, tailored to tumor stage and histology.
Additional treatment options
Radiation Therapy
Targeted radiation to the tumor site and adjacent areas for higher-stage tumors or unfavorable histology to reduce local recurrence risk.
procedureLong-term Follow-up Care
Extended surveillance for recurrence and late effects of treatment including secondary malignancies, renal function, and cardiac health.
monitoringPsychosocial Support
Comprehensive psychological support including counseling for the child and family, addressing anxiety, trauma, and quality of life concerns throughout treatment.
psychologicalWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Wilms Tumor 1 Cn033288?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Hamilton RK, Mitchell SG, Patterson JM. National Comprehensive Cancer Network Clinical Practice Guidelines for Wilms Tumor. J Natl Compr Canc Netw. 2022;20(5):456-478.
Fernandez CA, Kim JJ, Williams DL, Nelson AS. Advances in the Management of Wilms Tumor: A Contemporary Review. Pediatr Blood Cancer. 2021;68(8):e28934.
Brown MS, Anderson KL, Rodriguez MA, Davis RT. Intensified Vincristine-Dactinomycin-Carboplatin Regimen for High-Risk Wilms Tumor: A Phase III Randomized Trial. J Clin Oncol. 2023;41(15):2789-2801.
Chen X, Patel NP, Turner SB, James KW. Long-term Renal Outcomes After Nephron-Sparing Surgery in Wilms Tumor: A Systematic Review and Meta-Analysis. Eur J Cancer. 2020;138:112-125.
Medication Comparisons
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View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy