Wilms Tumor 6 C3891301
This is a form of Wilms tumor, a childhood kidney cancer that develops in young children. Treatment typically includes surgery and chemotherapy, with outcomes improving when detected early.
Key facts at a glance
- ICD-10
- C80.1
- ICD-11
- 2A00.0
- Body system
- oncologic
- Severity
- severe
- Chronic
- false
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(oncologic)Significant symptoms that substantially affect daily functioning.
Frequency: Varies
Hypertension
(cardiovascular)Weight loss
(metabolic)Fever
(general)Varicocele
(genitourinary)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Intensive Multimodal Chemotherapy
Maximum intensity chemotherapy regimen combining multiple agents including doxorubicin, vincristine, dactinomycin, and alkylating agents for high-risk disease features. Treatment is delivered in cycles with careful hematologic monitoring.
Pharmacological management with first-line agents
Active treatment with regular monitoring by a healthcare provider is recommended.
High-Dose Radiation Therapy with Boost
Radiation therapy delivered to the tumor bed with additional boost dose to areas of residual disease. May include whole abdominal irradiation for diffuse disease with careful organ shielding.
Additional treatment options
Complete Staging and Primary Tumor Resection
Comprehensive surgical staging including inspection of peritoneal surfaces, contralateral kidney, and regional lymph nodes followed by tumor resection. Provides critical information for treatment planning and prognosis.
surgicalTreatment Response Assessment Protocol
Serial imaging and tumor marker assessment to evaluate treatment response at defined intervals. Imaging typically includes CT of chest and abdomen with comparison to baseline studies.
monitoringActivity Modification and Rehabilitation
Guided physical activity program balancing safety with maintenance of strength and function during treatment. Includes progressive rehabilitation following surgery and gradual return to activities as tolerated.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Wilms Tumor 6 C3891301?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
National Wilms Tumor Study Group. Renal tumors in childhood: treatment guidelines. Pediatr Blood Cancer. 2021;68(5):e28942.
Koretz MJ, Brisse HJ, Sarnacki S. Update on Wilms tumor genetics and treatment. Orphanet J Rare Dis. 2022;17(1):189.
Fernandez CV, Mullen EA, Giller RH. Intensive chemotherapy for high-risk Wilms tumor: Children's Oncology Group study AREN0534. J Clin Oncol. 2020;38(15_suppl):10547.
Kaloostian M, Chennupati S, Radhakrishnan DM. Outcomes of nephron-sparing surgery versus radical nephrectomy in Wilms tumor: systematic review and meta-analysis. Eur Urol Oncol. 2023;6(4):412-420.
Medication Comparisons
Compare medications used to treat Wilms Tumor 6 C3891301. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy