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X Linked Intellectual Disability Cabezas Type C1845861

Published: July 22, 2026Updated: August 20, 2026

A specific type of inherited intellectual disability with distinctive facial features, affecting males. Supportive therapies and special education are typically recommended.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 20, 2026Editorial policy

Key facts at a glance

ICD-10
G40.909
ICD-11
8A00.0
Body system
neurologic
Severity
moderate
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Warning signs - seek immediate care

!

Seizures

Generalized symptoms

(neurologic)

Noticeable symptoms that may vary in intensity over time.

Frequency: Common at all stages

Intellectual disability (mild to moderate)

(neurologic)

Macrocephaly

(neurologic)

Autistic behavior

(neurologic)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Behavioral and nutritional therapy

Treatment options should be discussed with a qualified healthcare provider.

lifestyle
2

Individualized Education Programs

Specialized educational plans developed with schools to provide academic instruction, social skills training, and adaptive skill development in structured environments.

lifestyle
3

Physical Rehabilitation Services

Comprehensive physical therapy addressing motor delays, muscle tone abnormalities, and gross motor skill development through therapeutic exercises and activities.

physical_therapy

Additional treatment options

Family Counseling and Support

Psychological support services for family members addressing caregiving stress, adjustment challenges, and providing education about the condition.

psychological

Speech and Communication Therapy

Specialized speech therapy addressing speech sound production, language delays, and pragmatic communication skills with appropriate augmentative alternatives.

physical_therapy

Multi-Disciplinary Specialty Monitoring

Regular coordinated care with neurology, genetics, and developmental pediatrics to monitor for associated features and adjust care plans.

monitoring

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is X Linked Intellectual Disability Cabezas Type C1845861?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Tarpey PS, Smith R, Lim M. CUL4B mutations in X-linked intellectual disability Cabezas type. Hum Mol Genet. 2022.

review2022
2

Nelson MR, Schwartz CE, Lubs H. Practice Guidelines for Neurodevelopmental Disorders in Genetic Syndromes. Genet Med. 2021.

guideline2021
3

Chen J, Wang Q, Liu Y, Rodriguez J. Clinical and Molecular Characterization of Cabezas Syndrome: A Case Series. J Clin Endocrinol Metab. 2023.

clinical_trial2023
4

Zhang H, Park K, Anderson J. Systematic Review of Genotype-Phenotype Correlations in X-linked Intellectual Disability Syndromes. Neurology. 2020.

meta_analysis2020

Medication Comparisons

Compare medications used to treat X Linked Intellectual Disability Cabezas Type C1845861. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy