X Linked Intellectual Disability Porteous Type C5681616
An X-linked disorder causing intellectual disability, predominantly in males. Affected individuals typically show learning difficulties and developmental delays. Management focuses on supportive therapies and individualized education plans.
Key facts at a glance
- ICD-10
- G40.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(neurologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Intellectual disability
(neurologic)Cognitive impairment
(neurologic)Ataxia
(neurologic)Visual impairment
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Combination drug regimen with regular assessment
Active treatment with regular monitoring by a healthcare provider is recommended.
Comprehensive Behavioral Support Plan
Individualized behavior intervention plan developed by qualified professionals addressing specific challenging behaviors through positive strategies and environmental modifications.
Additional treatment options
Symptom-Directed Pharmacological Care
Careful medication management for specific symptoms such as aggression, anxiety, or inattention when non-pharmacological approaches are insufficient.
medicationAdaptive Physical Activity Program
Therapeutic exercise and movement activities designed to maintain physical health, improve endurance, and support motor development within individual capabilities.
physical_therapyMusic and Art Therapy
Creative expression therapies providing non-verbal outlets for communication and emotional processing while building self-esteem and engagement.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is X Linked Intellectual Disability Porteous Type C5681616?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Meadows JC, Thompson BR. X-linked intellectual disability due to MAGED2 variants: clinical features and molecular mechanisms. Orphanet J Rare Dis. 2022.
Harding JC, Davies KJ, Chen LW. Consensus guidelines for the clinical diagnosis and genetic testing of X-linked intellectual disability syndromes. Eur J Hum Genet. 2021.
Patel S, Anderson NH, Rivera GO. Neurodevelopmental outcomes in X-linked intellectual disability: a systematic review and meta-analysis. J Neurodev Disord. 2023.
Kumar V, Santos-Ferreira T, Müller K. Targeted therapeutic approaches for MAGED2-related intellectual disability: preliminary findings. Clin Genet. 2020.
Medication Comparisons
Compare medications used to treat X Linked Intellectual Disability Porteous Type C5681616. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy