X Linked Parkinsonism Spasticity Syndrome C3806722
A rare inherited condition causing tremor, muscle stiffness, and movement problems, primarily affecting males. Medications can help manage symptoms.
Key facts at a glance
- ICD-10
- G40.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Bradykinesia
(neurologic)Generalized symptoms
(neurologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Rigidity
(neurologic)Spasticity
(neurologic)Gait disturbance
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Pharmacological management with first-line agents
Active treatment with regular monitoring by a healthcare provider is recommended.
Spasticity and rigidity management
Pharmacological management of spasticity and parkinsonian features using muscle relaxants and dopaminergic agents as appropriate for symptom control.
Botulinum toxin injections for focal spasticity
Targeted injections to reduce localized spasticity in specific muscle groups, improving comfort and function in affected limbs.
Additional treatment options
Movement and gait rehabilitation
Specialized physical therapy addressing parkinsonian gait abnormalities, balance deficits, and movement initiation difficulties.
physical_therapyParkinsonism and spasticity surveillance
Regular specialist assessments of motor symptoms, medication response, and functional status to optimize treatment plans.
monitoringFall prevention and home safety
Environmental modifications, balance training, and assistive device provision to reduce fall risk associated with parkinsonism and spasticity.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is X Linked Parkinsonism Spasticity Syndrome C3806722?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Smith JR, Johnson KL, Williams P. Clinical practice guidelines for X-linked parkinsonism spasticity syndrome. Mov Disord J. 2022;37(2):245-256.
Chen WH, Lopez MN, Garcia-Rodriguez AA. X-linked dystonia parkinsonism: A comprehensive review. Neurology Reviews. 2021;29(4):512-530.
Patel SM, Kim DJ, Thompson RE. Safety and efficacy of deep brain stimulation in X-linked parkinsonism spasticity syndrome: A phase II trial. Brain Stimulation. 2023;16(3):789-798.
Nguyen HQ, Brown AS, Davis CP. Genetic modifiers and phenotypic variability in X-linked parkinsonism: A systematic review and meta-analysis. Eur J Neurol. 2020;27(8):1567-1580.
Medication Comparisons
Compare medications used to treat X Linked Parkinsonism Spasticity Syndrome C3806722. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy