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Serum or plasma mass concentration of serum amyloid A protein

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of a protein called serum amyloid A, which is produced by the liver and can rise in response to inflammation or infection.

Quick summary

["SAA helps identify inflammation, infections, or autoimmune conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
40809-6
Short code
11DC 1h p chal SerPl-mCnc
Synonyms
11DC 1h p chal SerPl-mCnc
Category
hormone
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is Serum Amyloid A (SAA) Used For?

SAA is often checked alongside other inflammatory markers to help diagnose conditions like infections (such as sepsis), inflammatory diseases (like rheumatoid arthritis), or fevers of unknown origin. It may also be used to monitor disease activity or response to treatment in some cases.

Why Might You Need This Test?

Your healthcare provider may order this test if you have symptoms like fever, fatigue, joint pain, or unexplained weight loss, or if you have a known condition that causes chronic inflammation. It can also be part of routine monitoring for certain chronic illnesses.

How Is the Test Performed?

A blood sample is drawn from a vein, usually in your arm. The blood is then processed to separate the serum or plasma, which is sent to a lab for testing. The results are typically ready within a few days.

What Do the Results Mean?

Higher than normal levels of SAA can signal inflammation or infection. Lower levels may suggest reduced inflammation or a lack of response to certain conditions. Your healthcare provider will interpret the results in the context of your overall health and medical history.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Serum Amyloid A (SAA) Level

Frequently asked questions

What causes SAA levels to be elevated?
SAA levels can rise due to infections (like bacterial or viral infections), chronic inflammatory diseases (such as rheumatoid arthritis or lupus), or other conditions causing prolonged inflammation, like certain cancers or autoimmune disorders.
How long does it take to get results from this test?
Test results are usually available within 2 to 5 business days, depending on your lab’s processing time. Your healthcare provider will contact you once the results are ready.
Can lifestyle changes affect SAA levels?
Yes, lifestyle factors like diet, exercise, and managing chronic conditions (such as diabetes or heart disease) can influence inflammation. Reducing stress, eating a balanced diet, and staying physically active may help support overall health and potentially affect inflammation markers like SAA.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy