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24-Hour Urine Substance Concentration (e.g., Creatinine)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of a specific substance in your urine collected over a full 24-hour period. It helps assess how much of the substance your body is producing or eliminating.

Quick summary

["A 24-hour urine test provides a complete picture of your body’s substance levels over time."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
34204-8
Short code
11DC 24h Ur-sCnc
Synonyms
11DC 24h Ur-sCnc
Category
hormone
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test to evaluate kidney function, detect imbalances in electrolytes, hormones, or other substances, or monitor conditions like kidney disease, metabolic disorders, or certain cancers. It can also help diagnose or manage conditions like diabetes, hypertension, or kidney stones.

How the Test Works

You’ll collect all urine for a full 24-hour period in a special container. The test measures the total amount of the substance in that urine sample, which reflects your body’s overall production and excretion over time.

Sample Collection

To prepare, empty your bladder at the start of the collection period (typically midnight to midnight). Then, collect every drop of urine for the next 24 hours, including during sleep. Store the urine in a refrigerator to keep it fresh. Bring the full container to your lab visit.

What to Expect

The test is usually painless and non-invasive. You’ll need to follow specific instructions to ensure accurate results, such as keeping the urine cold and completing the full 24-hour period. Some tests may require additional steps like special diet or medication adjustments.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

24h Urine Substance

Frequently asked questions

What does a 24-hour urine test measure?
A 24-hour urine test measures the total amount of a specific substance (like creatinine, sodium, or hormones) in your urine over a full day. The exact substance depends on your healthcare provider’s reason for testing.
How long does it take to get results?
Results typically take 1 to 2 weeks to be processed and reviewed by your healthcare provider, depending on lab workload. Follow-up may be needed if additional testing or evaluation is required.
Can I drink alcohol or certain medications during the test?
Avoid alcohol and some medications (like certain diuretics) unless instructed by your provider. Follow your healthcare team’s specific guidelines to ensure accurate results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy