Serum or plasma mass concentration of total protein
This test measures the total amount of protein in your blood, including albumin and other proteins like globulins. Proteins are essential for maintaining fluid balance, supporting immunity, and transporting nutrients.
["Total protein helps assess overall health, detect kidney issues, or identify protein-losing conditions."]
Key facts at a glance
- LOINC
- 57505-0
- Short code
- 11DC 2D p MTP SerPl-mCnc
- Synonyms
- 11DC 2D p MTP SerPl-mCnc
- Category
- hormone
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why It Matters in Your Health
Your body relies on proteins for many vital functions, including keeping fluids in the right places, fighting infections, and helping cells communicate. Blood protein levels can give clues about how well your organs are working, especially your kidneys or liver.
What Could Affect Your Results
Several factors may influence your protein levels, such as diet (high-protein foods like meat, dairy, or legumes), hydration status, chronic illnesses (like kidney disease or liver problems), or certain medications. Recent blood loss, dehydration, or severe infections can also temporarily change results.
Common Conditions Linked to Protein Levels
Low protein levels (hypoproteinemia) might signal kidney disease, liver failure, malnutrition, or conditions where your body loses protein (like severe diarrhea or vomiting). High protein levels could indicate dehydration, certain cancers, or overactive thyroid.
What to Expect During the Test
A simple blood draw is used to collect your serum or plasma. The sample is then analyzed to measure the total protein content. This test is quick and painless, usually done in a lab setting with minimal preparation needed beyond fasting if required by your doctor.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
Total Protein
Frequently asked questions
Why might my doctor order this test?
How long will I need to prepare for this test?
What are the typical reference ranges for this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy