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Total Protein with Albumin/Globulin Ratio (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures the total protein in your blood and evaluates the balance between albumin and globulin proteins, which are key to maintaining fluid balance and supporting immune function.

Quick summary

["Understanding your protein balance helps identify issues like malnutrition, liver disease, or immune disorders."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
57002-8
Short code
11DC 4D p chal SerPl-mCnc
Synonyms
11DC 4D p chal SerPl-mCnc
Category
hormone
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors may order this test to check for conditions affecting protein levels, such as kidney disease, liver problems, or chronic infections. It can also help monitor long-term health in patients with certain diseases.

What to Expect Before the Test

No special preparation is needed. You’ll have a small needle inserted into your arm for a blood draw, which usually takes just a few minutes. If you’re on blood thinners, let your doctor know before the test.

What the Results Mean

Total protein and albumin/globulin ratios help determine if your body is producing enough proteins or if there’s an imbalance. Abnormal results may signal underlying health concerns that need further evaluation.

Common Conditions Affecting Results

High protein levels might indicate dehydration, severe infections, or conditions like multiple myeloma. Low protein levels could signal malnutrition, liver disease, or kidney problems. Globulin levels may rise with chronic inflammation or autoimmune diseases.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test helps assess overall protein status, fluid balance, and immune function, guiding treatment for conditions like chronic kidney disease, liver cirrhosis, or immune disorders.

Short name

Protein Profile

Frequently asked questions

What causes abnormal protein levels in my blood?
Abnormal protein levels can result from conditions like kidney disease, liver problems, infections, or certain cancers. Diet, hydration status, and medications can also influence results. Always discuss symptoms with your doctor.
Do I need to fast before this test?
No fasting is required for this test. Blood is drawn from a vein, similar to other routine blood tests.
How long will it take to get my results?
Results are typically available within 1–3 business days, depending on your lab. Your doctor will explain them in detail during your follow-up visit.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy