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Urine Total Protein (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of protein found in your urine, which can help detect kidney problems or other conditions affecting protein loss in the body.

Quick summary

["A urine protein test helps identify potential kidney or systemic issues by checking for abnormal protein presence in urine."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
110615-2
Short code
11DC Msmt Ur
Synonyms
11DC Msmt Ur
Category
hormone
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you have symptoms like frequent urination, swelling in limbs, or unexplained weight changes. It’s also used to monitor kidney function in people with diabetes, high blood pressure, or a history of kidney disease.

What to Expect During the Test

You’ll likely collect a midstream urine sample (midstream clean-catch) or provide a timed 24-hour urine sample. No special preparation is needed unless instructed otherwise.

Possible Results and Interpretation

Higher-than-normal protein levels in urine may suggest kidney damage, proteinuria (excess protein in urine), or conditions like nephrotic syndrome. Lower-than-normal levels may indicate dehydration or normal protein excretion.

Common Conditions Monitored

This test helps diagnose or monitor kidney diseases, such as glomerulonephritis, diabetic nephropathy, or other conditions causing protein loss in urine.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated urine protein levels can signal kidney damage or dysfunction, which may require further evaluation (e.g., kidney biopsy, imaging). Early detection helps manage conditions like chronic kidney disease or systemic diseases affecting protein metabolism.

Short name

Urine Protein Test

Frequently asked questions

What causes protein in urine?
Protein in urine can result from kidney issues (e.g., damage to kidney filters), infections, certain medications, or conditions like pregnancy or high blood pressure. If you notice changes in urine appearance (e.g., foamy or cloudy), discuss it with your doctor.
A urine protein test specifically measures protein lost through urine, while a blood protein test (like albumin or total protein) checks protein levels in your bloodstream. Both serve different diagnostic purposes.
Dietary changes (e.g., high-protein diets) may temporarily influence urine protein levels, but results are typically interpreted in the context of clinical symptoms and other tests. Follow your provider’s instructions for fasting or dietary restrictions if applicable.
Yes, if your provider orders a 24-hour urine protein test, you’ll need to collect all urine for 24 hours in a special container. This provides a more accurate measure of daily protein excretion.
Cloudy or bloody urine may indicate infection, kidney stones, or another issue. See your healthcare provider promptly for evaluation, as these findings could affect your test results or require treatment.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy