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Serum Creatinine Concentration (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of creatinine, a waste product from muscle metabolism, in your blood serum. It helps assess kidney function.

Quick summary

["Kidney health and function depend on this simple blood test."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
57500-1
Short code
11DC pre MTP SerPl-sCnc
Synonyms
11DC pre MTP SerPl-sCnc
Category
hormone
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order this test to check how well your kidneys are filtering waste from your blood. It’s often used to monitor kidney disease, track chronic conditions like diabetes or heart disease, or evaluate kidney function before certain procedures.

What Does the Result Mean?

Higher than expected levels may indicate kidney problems, while lower levels could suggest muscle breakdown or other health issues. Your doctor will interpret the result in relation to your overall health and medical history.

How Is the Test Performed?

A blood sample is taken from a vein, usually in your arm. The sample is sent to a lab where it’s analyzed to measure creatinine concentration using a specialized method.

What Should You Do Before the Test?

Avoid strenuous exercise or heavy meals 24 hours before the test. If you’re on certain medications (like NSAIDs), discuss them with your doctor, as they may affect kidney function.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test plays a critical role in diagnosing and managing kidney disease, hypertension, and other conditions affecting blood flow and organ function. Elevated creatinine levels often signal impaired kidney filtration, prompting further evaluation or treatment adjustments.

Short name

Creatinine Level

Frequently asked questions

How often should I get this test?
Your doctor will determine how often you need this test based on your health status. For example, people with kidney disease or diabetes may need it more frequently than others.
Will I feel any pain or discomfort during the blood draw?
You may feel a slight pinch or sting when the needle is inserted, but it usually goes away quickly. Most people experience minimal discomfort afterward.
Can I eat or drink normally before this test?
Yes, you can eat and drink as usual unless your doctor has specific instructions. Avoiding fluids right before the test isn’t necessary unless advised otherwise.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy