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Serum or Plasma Creatinine Concentration (Electrochemiluminescence Immunoassay)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of creatinine, a waste product from muscle metabolism, in your blood or plasma. It helps assess kidney function.

Quick summary

["Kidney health check: creatinine levels help detect early kidney problems."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
50721-0
Short code
11DC sp1 p chal SerPl-mCnc
Synonyms
11DC sp1 p chal SerPl-mCnc
Category
hormone
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Creatinine is a byproduct of muscle breakdown and is filtered out by your kidneys. High levels may indicate reduced kidney function, while low levels could suggest dehydration or other conditions. This test is often used alongside other kidney-related tests to monitor overall kidney health.

What to Expect Before the Test

No special preparation is needed for this test. You may have a blood draw (serum/plasma) or, in some cases, a urine sample (though the slug indicates serum/plasma). Avoid excessive alcohol or strenuous activity 24 hours before testing if instructed by your provider.

Common Causes of Abnormal Results

Elevated creatinine levels may be due to kidney disease, dehydration, or conditions affecting muscle mass. Low levels might suggest dehydration, overhydration, or certain medical conditions. Always discuss symptoms or concerns with your healthcare provider.

When You Might Need This Test

Your doctor may order this test to evaluate kidney function, monitor chronic conditions (like diabetes or hypertension), or check for signs of kidney damage before surgeries or treatments.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Creatinine Level

Frequently asked questions

What does a ‘normal’ result mean?
A ‘normal’ result doesn’t mean your kidneys are perfectly healthy—it means your creatinine level falls within the expected range for your age, sex, and body size. Your doctor will interpret results in relation to your overall health and other test results.
Can diet affect creatinine levels?
Dietary changes alone won’t alter creatinine levels, but certain foods (like high-protein diets) or medications (e.g., NSAIDs) may indirectly impact kidney function. Always follow your doctor’s advice regarding dietary restrictions if prescribed.
How often should I get this test?
Frequency depends on your health status. People with kidney disease or risk factors (e.g., diabetes, hypertension) may need this test more often—typically every 3–12 months. Your doctor will determine the best schedule for you.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy