Skip to content

Understanding Your Medical Test: What It Is, Why It Is Done, and How to Get Ready

Published: August 9, 2026Updated: August 10, 2026

This test measures the level of 11-hydroxyandrostenedione, an androgen hormone produced mainly by the adrenal glands, in your blood to help evaluate adrenal gland function.

Quick summary

{"11-Hydroxyandrostenedione is an androgen hormone produced by the adrenal glands","This test helps doctors diagnose adrenal disorders like congenital adrenal hyperplasia or adrenal tumors","Blood is drawn from a vein in your arm for this test","No special preparation is usually needed, but follow your doctor's instructions","Results help assess conditions affecting hormone production"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 10, 2026Editorial policy

Key facts at a glance

LOINC
1658-4
Short code
11-OHAD
Synonyms
11OH-Ad SerPl-mCnc
Category
chemistry
Sample
serum
Container
Red top serum separator tube (SST) or plain red top tube
Units
N/A
Ref low
0.3
Ref high
2.8
Critical range
— – 10 N/A
Fasting
false
Population
adult
Sex
all
Age range
0–100 years
Method
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) or Immunoassay
CPT
82146
SNOMED
414589004
Specimen volume
1-2 mL serum minimum
Stability
Room temperature: 24 hours; Refrigerated (2-8°C): 7 days; Frozen (-20°C or below): 30 days; Protect from light
Hemolysis max
50
Lipemia max
300
Icterus max
20
TAT
24–72 hours
Order
routine

This test is a medical procedure that gives your healthcare provider important information about how your body is working. It can help detect a health condition, confirm or rule out a diagnosis, or monitor a problem you already know about.

The 11-Hydroxyandrostenedione (11-OHA) test measures the amount of a specific androgen hormone in your blood. 11-Hydroxyandrostenedione is produced primarily by the adrenal glands, which are small glands located on top of each kidney. This hormone is an intermediate product in the synthesis of other steroid hormones and plays a role in the body's hormonal balance.

Your provider orders this test to gather clues about symptoms you may be having, check for conditions that do not always cause obvious signs, measure how well a current treatment is working, or establish a baseline of your overall health for future comparison.

Your doctor may order this test to evaluate how well your adrenal glands are functioning. It is commonly used to help diagnose conditions that affect adrenal hormone production, such as congenital adrenal hyperplasia (a genetic disorder affecting hormone production), adrenal tumors, or other disorders of the adrenal glands. The test may also be used to investigate symptoms like abnormal hair growth, early puberty, or hormonal imbalances.

The test is performed by a trained member of your care team in a laboratory, clinic, or hospital setting. Depending on the type of test, it may involve providing a small sample of blood, urine, or other tissue, or it may use imaging equipment, and most tests take only a short time to complete.

A healthcare professional will draw a small sample of blood from a vein in your arm using a needle. The blood sample will be sent to a laboratory for analysis. The procedure is quick and usually takes only a few minutes. You may feel a slight sting when the needle is inserted or removed.

Follow any specific instructions your provider gives you before your appointment. You may be asked to fast for a certain number of hours, avoid certain foods, drinks, or medications, drink extra water, or schedule the test at a particular time of day. Tell your care team about all medications, supplements, and allergies you have, and bring your insurance card along with any questions you want to ask.

Your doctor will provide specific instructions. In general, you may need to fast (not eat or drink anything except water) for a certain period before the test. Some medications can affect hormone levels, so inform your doctor about all medications, supplements, or herbal remedies you are taking. Follow all instructions provided by your healthcare provider.

Reference range

Adult males: 0.6-2.8 ng/mL; Adult females: 0.3-2.0 ng/mL; Prepubertal children: 0.1-0.5 ng/mL; Pubertal: variable depending on Tanner stageN/A

Specimen: serum

No specific fasting required; avoid strenuous exercise and stress before collection; inform about current medications including glucocorticoids and hormonal contraceptives

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Frequently asked questions

Is the blood test painful?
You may feel a brief sting or pinch when the needle is inserted to draw blood. This discomfort is usually minor and temporary. After the needle is removed, you may have slight bruising or soreness at the injection site, which typically goes away quickly.
How long does it take to get results?
The time to receive results varies depending on the laboratory. It usually takes a few days to a week. Your healthcare provider will contact you with the results or discuss them at your follow-up appointment.
Are there any risks associated with this test?
The risks are minimal and include slight bleeding, bruising, or infection at the needle insertion site. Some people may feel lightheaded or dizzy during or after the blood draw. These risks are generally low and the procedure is considered safe.
Do I need to do anything special after the test?
After the test, you can resume your normal activities immediately. If you feel dizzy or lightheaded, sit and rest for a few minutes. Keep the bandage on for a short time as directed by your healthcare provider. Follow any specific instructions given by your doctor.
What do abnormal results mean?
Abnormal results do not always indicate a serious problem. Your doctor will interpret the results based on your symptoms, medical history, and other test results. Further testing may be needed to confirm a diagnosis. Always discuss your results with your healthcare provider to understand what they mean for your health.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 10, 2026. · Read our editorial policy