Understanding Your Medical Test: What It Is, Why It Is Done, and How to Get Ready
This test measures the level of 11-hydroxyandrostenedione, an androgen hormone produced mainly by the adrenal glands, in your blood to help evaluate adrenal gland function.
{"11-Hydroxyandrostenedione is an androgen hormone produced by the adrenal glands","This test helps doctors diagnose adrenal disorders like congenital adrenal hyperplasia or adrenal tumors","Blood is drawn from a vein in your arm for this test","No special preparation is usually needed, but follow your doctor's instructions","Results help assess conditions affecting hormone production"}
Key facts at a glance
- LOINC
- 1658-4
- Short code
- 11-OHAD
- Synonyms
- 11OH-Ad SerPl-mCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red top serum separator tube (SST) or plain red top tube
- Units
- N/A
- Ref low
- 0.3
- Ref high
- 2.8
- Critical range
- — – 10 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 0–100 years
- Method
- Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) or Immunoassay
- CPT
- 82146
- SNOMED
- 414589004
- Specimen volume
- 1-2 mL serum minimum
- Stability
- Room temperature: 24 hours; Refrigerated (2-8°C): 7 days; Frozen (-20°C or below): 30 days; Protect from light
- Hemolysis max
- 50
- Lipemia max
- 300
- Icterus max
- 20
- TAT
- 24–72 hours
- Order
- routine
This test is a medical procedure that gives your healthcare provider important information about how your body is working. It can help detect a health condition, confirm or rule out a diagnosis, or monitor a problem you already know about.
The 11-Hydroxyandrostenedione (11-OHA) test measures the amount of a specific androgen hormone in your blood. 11-Hydroxyandrostenedione is produced primarily by the adrenal glands, which are small glands located on top of each kidney. This hormone is an intermediate product in the synthesis of other steroid hormones and plays a role in the body's hormonal balance.
Your provider orders this test to gather clues about symptoms you may be having, check for conditions that do not always cause obvious signs, measure how well a current treatment is working, or establish a baseline of your overall health for future comparison.
Your doctor may order this test to evaluate how well your adrenal glands are functioning. It is commonly used to help diagnose conditions that affect adrenal hormone production, such as congenital adrenal hyperplasia (a genetic disorder affecting hormone production), adrenal tumors, or other disorders of the adrenal glands. The test may also be used to investigate symptoms like abnormal hair growth, early puberty, or hormonal imbalances.
The test is performed by a trained member of your care team in a laboratory, clinic, or hospital setting. Depending on the type of test, it may involve providing a small sample of blood, urine, or other tissue, or it may use imaging equipment, and most tests take only a short time to complete.
A healthcare professional will draw a small sample of blood from a vein in your arm using a needle. The blood sample will be sent to a laboratory for analysis. The procedure is quick and usually takes only a few minutes. You may feel a slight sting when the needle is inserted or removed.
Follow any specific instructions your provider gives you before your appointment. You may be asked to fast for a certain number of hours, avoid certain foods, drinks, or medications, drink extra water, or schedule the test at a particular time of day. Tell your care team about all medications, supplements, and allergies you have, and bring your insurance card along with any questions you want to ask.
Your doctor will provide specific instructions. In general, you may need to fast (not eat or drink anything except water) for a certain period before the test. Some medications can affect hormone levels, so inform your doctor about all medications, supplements, or herbal remedies you are taking. Follow all instructions provided by your healthcare provider.
Reference range
Adult males: 0.6-2.8 ng/mL; Adult females: 0.3-2.0 ng/mL; Prepubertal children: 0.1-0.5 ng/mL; Pubertal: variable depending on Tanner stageN/A
No specific fasting required; avoid strenuous exercise and stress before collection; inform about current medications including glucocorticoids and hormonal contraceptives
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Frequently asked questions
Is the blood test painful?
How long does it take to get results?
Are there any risks associated with this test?
Do I need to do anything special after the test?
What do abnormal results mean?
Sources
- 1
- 2
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 10, 2026. · Read our editorial policy