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14dioxaneserplql

Published: August 9, 2026Updated: August 16, 2026

This test checks for the presence of 1,4-dioxane, a potentially harmful chemical, in your blood.

Quick summary

{"1,4-Dioxane is an industrial chemical that may cause cancer with long-term exposure","This test is mainly used for workers who handle this chemical on the job","Results show whether you have been exposed to 1,4-dioxane through your work or environment","The test requires a simple blood draw from your arm","If you work with solvents or cleaning products, your employer may require this test"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
27423-3
Short code
DIOX
Synonyms
1,4Dioxane SerPl Ql
Category
chemistry
Sample
serum
Container
Serum separator tube (SST) or plain red top tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
≥ 18 years
Method
Gas Chromatography-Mass Spectrometry (GC-MS) or Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
CPT
84600 (may vary by methodology)
SNOMED
122465000
Specimen volume
2-3 mL serum
Stability
Room temperature: 24 hours; Refrigerated (2-8°C): 7 days; Frozen (-20°C or below): 30 days
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
72–168 hours
Order
routine

What is this test?

The 1,4-Dioxane blood test detects whether this chemical is present in your bloodstream. 1,4-Dioxane is a clear liquid used in industrial processes, particularly as a solvent for dyes, oils, and greases. It is also found in some consumer products like cosmetics, detergents, and cleaning agents. The test is typically ordered for workers in industries where 1,4-Dioxane is used or produced, as part of occupational health monitoring programs.

How is the test performed?

A healthcare professional will draw a small sample of blood from a vein in your arm. The blood sample will be collected in a special tube and sent to a laboratory for analysis. You do not need to fast or prepare specially for this test. The blood sample will be tested to determine whether 1,4-Dioxane is present in your system.

What do the results mean?

A "negative" or "not detected" result means 1,4-Dioxane was not found in your blood at the time of testing. A "positive" or "detected" result indicates that you have been exposed to 1,4-Dioxane. Your healthcare provider or occupational health specialist will explain what this means for your specific situation and whether any follow-up actions are needed.

Reference range

Not DetectedN/A

Specimen: serum

No special preparation required. Avoid exposure to products containing 1,4-dioxane (certain cosmetics, detergents, adhesives) for 24-48 hours before sample collection if possible. Inform laboratory of any occupational or environmental exposure history.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Frequently asked questions

Why do I need this test?
This test is usually ordered if you work in an industry where 1,4-Dioxane is used, such as chemical manufacturing, textile processing, or certain cleaning product production. It helps your employer monitor workplace safety and ensure you are not being exposed to dangerous levels of this chemical.
Is the test painful?
You may feel a brief sting or pinch when the needle is inserted to draw blood. This is similar to other routine blood tests. The discomfort is usually minimal and only lasts a few seconds.
How long does it take to get results?
Test results typically take a few days to a week, depending on the laboratory. Your healthcare provider or occupational health department will inform you when results are available.
What should I do if my result is positive?
If 1,4-Dioxane is detected in your blood, discuss the result with your healthcare provider or occupational health specialist. They will evaluate your exposure level and recommend appropriate steps, which may include reviewing your workplace safety procedures, using additional protective equipment, or making changes to your work environment.
Can I reduce my exposure to 1,4-Dioxane?
If you work with this chemical, follow all workplace safety guidelines, use provided protective equipment such as gloves and respirators, and participate in any safety training programs. If you are concerned about environmental exposure, check local water quality reports and use filtered water if contamination is suspected.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy