17-Hydroxyandrostenedione and Androstenedione (Serum/Plasma)
This test measures two hormones produced by your adrenal glands and ovaries/testes. They help regulate energy, sex hormones, and metabolism.
["These hormones may affect your adrenal health, hormone balance, and how your body uses energy."]
Key facts at a glance
- LOINC
- 53336-4
- Short code
- 17OHCS+Androst/Cortis DBS
- Synonyms
- 17OHCS+Androst/Cortis DBS
- Category
- hormone
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your doctor may recommend this test to check for conditions like adrenal tumors, hormonal imbalances, or to monitor treatment for conditions like Cushing’s syndrome or congenital adrenal hyperplasia. It could also be part of a broader evaluation for infertility or metabolic disorders.
What the Results Typically Mean
Elevated levels might suggest overactivity of your adrenal glands or certain genetic conditions. Lower-than-expected levels could indicate underactivity or other hormonal issues. Your doctor will interpret results in the context of your overall health and symptoms.
Sample Collection and Preparation
A blood sample is drawn from a vein in your arm. You may feel a slight pinch, but it usually doesn’t cause significant discomfort. The blood is then sent to a lab for testing. No special preparation is needed, but avoid eating or drinking for a few hours before the test if instructed.
Common Conditions Monitored
This test helps diagnose or manage conditions such as adrenal tumors, polycystic ovary syndrome (PCOS), or congenital adrenal hyperplasia. It may also be used to assess hormonal imbalances in people with metabolic disorders or those undergoing fertility treatments.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
17OHCS & Androstenedione
Frequently asked questions
What does a high level of 17-hydroxyandrostenedione or androstenedione mean?
What does a low level of these hormones mean?
How often should I get this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy