6-Alpha-Hydroxytestosterone/Creatinine, Urine — Screening Ratio
A specialized urine test that measures 6-alpha-hydroxytestosterone, a steroid metabolite, and may compare it with urine creatinine.
["This test evaluates a urinary steroid metabolite that can help assess adrenal hormone production and metabolism."]
Key facts at a glance
- LOINC
- 44864-7
- Short code
- 6A-OH-THS/Creat Ur
- Synonyms
- 6A-OH-THS/Creat Ur
- Category
- liver
- Sample
- urine
- Container
- Sterile urine container
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 10 mL
- Stability
- Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
What is this test?
This is a screening test for 6-alpha-hydroxytestosterone in urine. This substance is a metabolite formed during steroid hormone metabolism. Urine creatinine may be measured at the same time to help account for how concentrated or dilute the urine sample is.
Why might I need this test?
A clinician may order this specialized test when evaluating unusual hormonal symptoms or suspected differences in adrenal steroid production. It is not usually part of routine testing and is generally interpreted by a clinician familiar with steroid disorders.
How is the test performed?
You provide a urine sample in the container supplied by the laboratory. The laboratory measures 6-alpha-hydroxytestosterone and may determine urine creatinine so the result can be expressed as a ratio or otherwise adjusted for urine concentration.
How do I prepare for the test?
Follow the laboratory's collection instructions, including whether a first-morning or timed urine sample is required. Do not stop prescribed medicines or take extra hormones without medical guidance, because corticosteroids and other hormonal medicines can affect the results.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Abnormal levels may indicate altered steroid hormone production or metabolism, including certain uncommon endocrine disorders. Results can also be influenced by illness, stress, puberty, medications, and temporary changes in urine concentration. The result should be interpreted with symptoms, medical history, and other laboratory tests rather than used alone to make a diagnosis.
Short name
Urinary 6-alpha-hydroxytestosterone screen
Frequently asked questions
Is this the same as a standard testosterone test?
Do I need to fast for this urine test?
Can one abnormal result diagnose a hormone disorder?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy