Alpha-1 Antitrypsin, Dried Stool — Mass Concentration

What is this test?

This test measures the amount of alpha-1 antitrypsin, a blood protein, in a dried stool sample. Alpha-1 antitrypsin is normally present in the digestive tract, and increased amounts in stool can occur when protein is lost through the intestinal lining.

Why might I need this test?

A clinician may order this test when symptoms suggest protein-losing enteropathy, a condition in which the intestine leaks blood proteins into the digestive tract. It may be used in the evaluation of unexplained swelling, low blood protein, or intestinal inflammation alongside other laboratory tests.

How is the test performed?

You collect a stool sample and place it in the container provided by the laboratory. The laboratory measures the alpha-1 antitrypsin concentration in the dried stool specimen and reports the result, which your clinician interprets with your symptoms and other findings.

How do I prepare for the test?

Before collecting the sample, follow the laboratory's instructions and ask whether any diet or medication changes are required. Collect fresh stool in the supplied container without adding water, urine, toilet paper, or cleaner, and provide the amount and collection time requested.