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Allergen-Specific IgE (RAST), Serum

Published: August 9, 2026Updated: August 17, 2026

A blood test that measures IgE antibodies to selected allergens. It may help identify triggers related to allergy symptoms.

Quick summary

["This test can help determine whether specific allergens are likely triggers of your allergy symptoms."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
102136-9
Short code
A alternata IgE RAST
Synonyms
A alternata IgE RAST
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
7
Ref high
56
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
rast
CPT
84484
SNOMED
302773008
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This test, also called the radioallergosorbent test (RAST), measures allergen-specific IgE antibodies in a blood sample. IgE is an immune-system protein that can react with particular substances such as pollen, foods, dust mites, or animal dander.

Why might I need this test?

Your clinician may order this test to help evaluate allergy symptoms such as sneezing, wheezing, hives, or swelling. The results can help identify possible triggers and guide further allergy evaluation or treatment.

How is the test performed?

A blood sample is collected and tested in a laboratory for antibodies against selected allergens. The report usually identifies the allergens tested and gives a result for each one.

How do I prepare for the test?

Fasting is generally not required. Tell your clinician about all medicines and supplements you take because antihistamines and certain other treatments may affect test results; do not stop prescribed medication without medical advice.

Reference range

Adult males: 7-56 U/L; Adult females: 7-43 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

A detectable allergen-specific IgE result indicates that your immune system has produced antibodies against that allergen, but it does not by itself prove that the allergen causes your symptoms. Results can also be positive without current allergy symptoms, so they should be interpreted alongside your medical history and examination. Your clinician may recommend additional allergy testing when needed.

Short name

Allergen-Specific IgE (RAST)

Frequently asked questions

Does a positive result mean I am allergic to that substance?
Not always. It shows that IgE antibodies to the substance are present, so clinical symptoms and other test findings are needed to determine whether there is a true allergy.
Can this test identify every possible allergen?
No. It measures only the allergens included in the ordered panel, so a negative or low result for those allergens does not rule out reactions to other substances.
Should I stop taking allergy medicine before the test?
Discuss this with your clinician first. Some antihistamines and other allergy treatments can affect the results, and your clinician can advise whether any temporary medication change is appropriate.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy