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Platelet Glycoprotein IIb/IIIa (GPIIb/IIIa) Antigen Level

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of specific proteins (glycoprotein IIb/IIIa) on the surface of your platelets, which play a key role in blood clotting.

Quick summary

["Understanding your platelet protein levels can help assess bleeding risks or response to certain medications."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
73555-5
Short code
Abciximab ind plt IgG SerPl Ql FC
Synonyms
Abciximab ind plt IgG SerPl Ql FC
Category
hematology
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
flow-cytometry
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have concerns about abnormal bleeding, clotting disorders, or if you’re receiving medications like abciximab (ReoPro), which affect platelet function. It can also help monitor platelet activity in people with conditions like von Willebrand disease or thrombocytopenia.

What to Expect Before the Test

No special preparation is needed. A blood sample will be taken from a vein, usually in your arm. You may feel a slight pinch, but it’s quick and painless. If you’re on blood-thinning medications, let your provider know before the test.

What the Results Mean

Lower than expected levels may indicate too few platelets or impaired platelet function, while higher levels could suggest conditions like thrombocytosis or certain blood disorders. Your results will be compared to what’s typical for healthy adults.

Common Causes of Abnormal Results

Factors like medications (e.g., abciximab), infections, or underlying blood disorders can affect GPIIb/IIIa levels. Repeated testing may be needed to track changes over time.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

GPIIb/IIIa Antigen

Frequently asked questions

What does a low GPIIb/IIIa level mean?
A low level may suggest reduced platelet function, which could increase bleeding risk—especially if you’re on medications that affect clotting. Your provider may adjust treatments or monitor you closely.
Could high levels indicate a problem?
High levels might be seen in conditions like thrombocytosis or certain cancers, but they’re less common. Your provider will consider your full medical picture and other test results to interpret this.
How often should I get this test?
Your provider will determine the timing based on your treatment plan. If you’re on abciximab or other platelet-modifying drugs, testing may be done more frequently to ensure safety.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy