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Published: August 9, 2026Updated: August 10, 2026

This test monitors changes in your blood type after receiving a stem cell transplant to ensure safe blood transfusions.

Quick summary

{"After stem cell transplant, your blood type may change to match your donor's blood type","Regular testing ensures blood transfusions are safe and compatible","The test checks both ABO and Rh blood group systems","Results help your healthcare team provide the correct blood type for transfusions"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 10, 2026Editorial policy

Key facts at a glance

LOINC
93933-0
Short code
ABO/Rh Post-BMT
Synonyms
ABO+Rh Gp Pnl p stem trnsplt Bld
Category
chemistry
Sample
serum
Container
EDTA lavender top tube (K2-EDTA) preferred; ACD (yellow top) tube also acceptable
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
0–150 years
Method
Serum agglutination techniques including ABO forward typing (red cell antigens) and Rh typing (D antigen), with confirmatory testing for post-transplant chimerism monitoring
CPT
86900 (ABO typing), 86901 (Rh typing), 86850 (antibody screen post-transplant)
SNOMED
59321007 (blood typing procedure)
Specimen volume
Minimum 2 mL, optimal 3-5 mL of whole blood
Stability
Room temperature (20-24°C): 72 hours; Refrigerated (2-8°C): 7 days. Do not freeze whole blood specimen. For prolonged delays, separate plasma/serum and store at 2-8°C.
Hemolysis max
50
Lipemia max
400
Icterus max
25
TAT
1–24 hours
Order
routine

What is this test?

The ABO and Rh group test after hematopoietic stem cell transplant is a blood test that checks your blood type. After a stem cell transplant, the new stem cells from your donor will produce red blood cells that may have a different blood type than what you had before. This test helps your healthcare team track these changes and ensure you receive the correct blood type if you need a transfusion.

How is the test performed?

A healthcare professional will draw a small blood sample from a vein in your arm. The blood sample is sent to a laboratory where technicians will determine your ABO blood type (A, B, AB, or O) and your Rh status (positive or negative). The test is simple and takes only a few minutes to collect the sample.

Why is this test important after transplant?

Stem cell transplants replace your bone marrow with donor cells. These new cells produce red blood cells carrying the donor's blood group antigens. Over time, your blood type may gradually change to match your donor's blood type. This process is called chimerism. Regular testing helps your doctors know your current blood type so they can give you the right blood products if you need transfusions during your recovery.

How often will I need this test?

Your doctor will determine how often you need this test. It is typically done regularly during the first few months after your transplant, and then less frequently as your blood type stabilizes. Follow your transplant team's recommended testing schedule.

Reference range

Expected results: ABO blood group (A, B, AB, or O) and Rh status (Rh-positive or Rh-negative). Post-transplant patients may show mixed chimerism with dual populations or conversion to donor血型. Reference range indicates presence of expected ABO/Rh antigens based on donor/recipient status.N/A

Specimen: serum

No fasting required. Inform laboratory of recent transfusions (within 3 months), as donor red cells may interfere with typing. Provide complete transplant history including date of hematopoietic stem cell transplant, donor ABO/Rh type, and any recent transfusion products. Verify patient identity using two patient identifiers per CAP/CLIA requirements.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Frequently asked questions

Will my blood type definitely change after transplant?
Not always. Some patients maintain their original blood type if the donor and recipient have compatible blood types. However, if the donor has a different ABO or Rh type, your blood type will likely change over time as the donor's stem cells take over blood cell production.
How long does it take for blood type to change?
The timeline varies from patient to patient. Blood type conversion can occur within a few weeks to several months after transplant. Some patients may have a mixed blood type for a period of time before fully converting to the donor's type.
Does this test hurt?
You may feel a brief pinch or sting when the needle is inserted to draw blood. This is similar to any routine blood draw. The discomfort is usually minimal and lasts only a few seconds.
Do I need to fast before this test?
No fasting is required for this test. You can eat and drink normally before your blood draw.
What happens if my blood type doesn't match before a transfusion?
Your healthcare team will always verify your current blood type before giving any blood transfusion. They will use your most recent test results to ensure you receive the correct and safest blood type for your body.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 10, 2026. · Read our editorial policy