Skip to content

Acenocoumarolurmcnc

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of acenocoumarol, an anticoagulant (blood thinner) medication, in your urine.

Quick summary

{"Acenocoumarol is a blood-thinning medication used to prevent blood clots","This test checks how much of the drug is in your urine","It helps doctors monitor if you're taking the right dose","The test is simple and uses a urine sample","Results help ensure your treatment is safe and effective"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
78775-4
Short code
ACEN-UR
Synonyms
Acenocoumarol Ur-mCnc
Category
chemistry
Sample
urine
Container
Clean, sterile, labeled urine container (plastic or glass) without preservatives
Units
N/A
Ref low
0.1
Ref high
2
Critical range
0.05 N/A – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
≥ 18 years
Method
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) or High-Performance Liquid Chromatography (HPLC) with UV detection
CPT
80375
SNOMED
385058005
Specimen volume
Minimum 10 mL, preferred 20-50 mL
Stability
Room temperature: 24 hours; Refrigerated (2-8°C): 7 days; Frozen (-20°C): 30 days. Protect from light.
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
24–72 hours
Order
routine

What is this test?

The Urine Acenocoumarol test measures the concentration of acenocoumarol in your urine. Acenocoumarol is an anticoagulant medication, commonly known as a blood thinner. It belongs to a class of drugs called vitamin K antagonists, which help prevent the formation of dangerous blood clots in your blood vessels.

Why is this test performed?

This test is performed to monitor acenocoumarol levels in patients who are taking this medication for conditions such as deep vein thrombosis (DVT), pulmonary embolism (PE), atrial fibrillation, or after certain surgeries like heart valve replacement. Regular monitoring helps ensure the drug is working effectively and that the dose is appropriate for you.

How is the test done?

A urine sample is collected in a sterile container. You may be asked to provide a first-morning sample or a random urine sample, depending on your doctor's instructions. The sample is then sent to a laboratory where it is analyzed using specialized equipment to measure the acenocoumarol concentration.

Are there any risks?

This test involves collecting a urine sample, which is generally safe and has no significant risks. The procedure is non-invasive and does not cause any pain or discomfort.

What do the results mean?

Your test results will show the amount of acenocoumarol in your urine. Your doctor will interpret these results along with other tests (such as INR - International Normalized Ratio) to determine if your current medication dose is appropriate. Too little medication may not prevent clots effectively, while too much may increase your risk of bleeding.

Reference range

Therapeutic monitoring: 0.1-2.0 mcg/mL (patient-specific based on INR target); Non-detectable levels indicate non-compliance or subtherapeutic dosingN/A

Specimen: urine

Collect clean-catch midstream urine sample. Inform laboratory of current acenocoumarol dosage and timing of last dose. No fasting required. Avoid contamination with toilet paper or fecal material.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Frequently asked questions

Do I need to fast before this test?
No, fasting is not required for this test. You can eat and drink normally before providing the urine sample. However, follow any specific instructions given by your healthcare provider.
Can I take my acenocoumarol medication before the test?
Take your medication as prescribed by your doctor unless instructed otherwise. The timing of your dose in relation to the test may be important, so ask your healthcare provider for specific instructions.
How often do I need this test?
The frequency of this test depends on your individual condition and how stable your medication levels are. Your doctor will determine how often you need testing based on your specific situation.
What should I tell my doctor before the test?
Inform your doctor about all medications you are taking, including prescription drugs, over-the-counter medicines, vitamins, and supplements. Certain substances may affect the test results.
What happens if my acenocoumarol level is too high or too low?
If your level is too high, you may be at increased risk of bleeding, and your doctor may reduce your dose. If your level is too low, you may not be adequately protected against blood clots, and your dose may be increased. Your doctor will adjust your treatment plan based on these results.
  1. 1
    MedlinePlus - AnticoagulantsSource
  2. 2
    Mayo Clinic - Blood ThinnersSource
  3. 3
    Lab Tests Online - Therapeutic Drug MonitoringSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy