Complete Blood Count (CBC) Test
A breath test that detects acetone levels in your exhaled breath, commonly used to monitor metabolic conditions like diabetes.
{"Measures acetone in breath to check fat metabolism","Helps monitor diabetes and ketogenic diets","Non-invasive test using a special breathalyzer device","High acetone may indicate diabetic ketoacidosis","Results are ready immediately after the test"}
Key facts at a glance
- LOINC
- 5566-5
- Short code
- ACET
- Synonyms
- Acetone ExG Ql
- Category
- chemistry
- Sample
- serum
- Container
- Direct breath collection into specialized collection device or Tedlar bag
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- ≥ 0 years
- Method
- Gas chromatography-mass spectrometry (GC-MS) or enzymatic assay for detection of acetone in breath samples
- CPT
- 82040
- SNOMED
- 414189005
- Specimen volume
- Single breath exhalation or multiple breath samples
- Stability
- Analyze within 24 hours; some methods allow up to 72 hours at 2-8°C
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 24–72 hours
- Order
- routine
A complete blood count (CBC) is a common blood test that measures the different cells in your blood, including red blood cells, white blood cells, and platelets. It helps your doctor evaluate your overall health and screen for a wide range of conditions, such as anemia, infections, and blood disorders.
The breath acetone test measures the presence of acetone in your exhaled breath. Acetone is a chemical produced when your body breaks down fat for energy. When fats are metabolized faster than usual, excess acetone enters your bloodstream and is released when you breathe out. This test uses a specialized device similar to a breathalyzer to detect acetone levels in your breath.
The test is performed by drawing a small sample of blood from a vein, usually on the inside of your elbow. A healthcare professional will clean the skin, wrap a band around your arm, insert a thin needle, and collect the blood into a tube. The procedure usually takes only a few minutes.
The test is simple and non-invasive. You will be asked to breathe into a disposable mouthpiece connected to a breathalyzer device. The device analyzes the chemical compounds in your breath and measures acetone concentration. The test typically takes only a few minutes and does not require any blood draws or special preparation. You may be asked to fast or avoid certain foods before the test for accurate results.
Your results show whether your blood cell counts are within normal ranges. Values that are too high or too low may point to conditions such as anemia, infection, inflammation, clotting problems, or blood cancers. Your doctor will interpret the numbers together with your symptoms, medical history, and other test results.
Normal breath acetone levels are typically very low (less than 1 part per million). Elevated levels may indicate that your body is using fat for energy instead of glucose, which can occur in situations like fasting, prolonged exercise, or following a very low-carbohydrate diet. In people with diabetes, high acetone levels may signal diabetic ketoacidosis (DKA), a serious condition that requires immediate medical attention.
This test has very few risks. You may feel a brief sting or pinch when the needle is inserted, and the puncture site may be slightly sore or bruised for a day or two. Serious complications, such as heavy bleeding or infection at the site, are rare.
The breath acetone test is completely safe and non-invasive. There are no known risks or side effects associated with this test. It is painless and does not involve any needles or radiation exposure.
Reference range
Negative: Acetone not detected; Positive: Acetone detected above thresholdN/A
Patient should avoid alcohol, mouthwash, and breath fresheners for at least 15 minutes before collection. Avoid smoking and eating for 30 minutes prior to test. Inform healthcare provider of any ketogenic diet, fasting, or diabetes medications.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Breath acetone testing is clinically valuable for monitoring metabolic health. In diabetes management, it helps detect early signs of diabetic ketoacidosis, a potentially life-threatening complication. The test is also used to assess the effectiveness of weight loss programs, particularly ketogenic diets, by monitoring fat metabolism. Athletes may use it to optimize their metabolic state during training. Additionally, it can help differentiate between diabetic ketoacidosis and other causes of metabolic acidosis in clinical settings.
Frequently asked questions
Do I need to fast before the test?
Can I eat or drink before the test?
Is the test painful?
What can cause false high results?
How long does it take to get results?
Sources
- 1
- 2
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy