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Acetoneserplqlscn

Published: August 9, 2026Updated: August 15, 2026

A screening test to detect the presence of acetone (a type of ketone body) in your blood, used to evaluate metabolic conditions.

Quick summary

{"Measures acetone levels in blood to check for abnormal fat metabolism","Helps diagnose and monitor diabetic ketoacidosis (DKA)","Often ordered when someone has symptoms like nausea, vomiting, or rapid breathing","Results are typically reported as positive or negative (presence/absence)","A simple blood draw is all that's needed for this test"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 15, 2026Editorial policy

Key facts at a glance

LOINC
20469-3
Short code
ACET
Synonyms
Acetone SerPl Ql Scn
Category
chemistry
Sample
serum
Container
Serum separator tube (SST) or plain red top tube; plasma collection tube (EDTA or sodium fluoride)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
≥ 0 years
Method
screen
CPT
80378
SNOMED
415571006
Specimen volume
1.0-2.0 mL serum or plasma minimum
Stability
Room temperature: 24 hours; Refrigerated (2-8°C): 72 hours; Frozen (-20°C): 2 weeks. Separate serum/plasma from cells within 2 hours of collection.
Hemolysis max
50
Lipemia max
100
Icterus max
20
TAT
24–48 hours
Order
routine

What is this test?

The Acetone Presence test is a screening test that checks whether acetone is present in your blood serum or plasma. Acetone is a type of ketone body that your body produces when it breaks down fat for energy instead of using glucose (sugar). This test uses a screening method to detect if acetone is present above normal levels.

Why do I need this test?

Your doctor may order this test if you have symptoms suggesting ketoacidosis, a serious condition where too many ketones build up in the blood. Symptoms may include excessive thirst, frequent urination, nausea, vomiting, abdominal pain, rapid breathing, confusion, or fruity-smelling breath. This test is commonly used to monitor patients with diabetes, especially those with type 1 diabetes, to prevent or detect diabetic ketoacidosis (DKA).

How is the test done?

A healthcare professional will draw a small sample of blood from a vein in your arm using a needle. The blood will be collected in a tube and sent to a laboratory for analysis. You do not need to fast before this test unless your doctor specifically instructs you to. The test itself is quick, and you may experience minor discomfort or bruising at the puncture site.

Understanding your results

Results are typically reported as either 'Positive' (acetone is present) or 'Negative' (acetone is not detected). A positive result may indicate that your body is producing too many ketones, which could signal diabetic ketoacidosis, starvation, excessive alcohol consumption, or a very low-carbohydrate diet. Your doctor will interpret the results in the context of your symptoms, medical history, and other test results.

Reference range

Negative - No acetone detected; Positive - Acetone detected above thresholdN/A

Specimen: serum

No special preparation required. Fasting is not mandatory but may be physician-directed based on clinical indication.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Frequently asked questions

Do I need to fast before the test?
Typically, no fasting is required for this test. However, follow any specific instructions provided by your doctor, as they may have reason to ask you to fast based on your individual situation.
What does a positive result mean?
A positive result means acetone was detected in your blood. This could indicate diabetic ketoacidosis, starvation, excessive alcohol consumption, or a very low-carb diet. Your doctor will need to interpret this result along with your symptoms and other test findings.
Is this test painful?
You may feel a brief sting or pinch when the needle is inserted to draw blood. This is generally well-tolerated, and any discomfort usually goes away quickly. Some people may experience minor bruising at the site.
How long does it take to get results?
Results are usually available within a day or two, depending on the laboratory. Your doctor's office will contact you with the results or discuss them at your follow-up appointment.
Can I monitor ketone levels at home?
Yes, there are home testing kits available that can measure ketone levels in blood or urine. These are particularly useful for people with diabetes. However, home tests may not be as precise as laboratory tests. Always discuss any home testing with your doctor to ensure proper interpretation.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 15, 2026. · Read our editorial policy