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Acetonetmurmcnc

Published: August 9, 2026Updated: August 16, 2026

A urine test that measures acetone levels to help monitor ketone production in the body.

Quick summary

{"Acetone is a ketone body produced when the body burns fat for energy instead of glucose","This test is commonly used to monitor diabetes and detect diabetic ketoacidosis (DKA)","Positive results may indicate diabetes complications, fasting, or a ketogenic diet","The test involves collecting a urine sample for laboratory analysis","Results are reported qualitatively (positive/negative) rather than as a numeric value"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
35665-9
Short code
ACETONE
Synonyms
Acetone ?Tm Ur-mCnc
Category
chemistry
Sample
urine
Container
Sterile urine container (plastic or glass)
Units
N/A
Ref low
0
Ref high
1
Critical range
— – 20 N/A
Fasting
false
Population
adult
Sex
all
Age range
≥ 0 years
Method
Enzymatic or colorimetric assay
CPT
80378
SNOMED
271588005
Specimen volume
5-10 mL preferred
Stability
Room temperature: 24 hours; Refrigerated (2-8°C): 72 hours; Frozen (-20°C): 2 weeks
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
2–24 hours
Order
routine

What is this test?

The urine acetone test measures the amount of acetone (a type of ketone body) in your urine. Ketones are produced when your body breaks down fat for energy, which typically happens when there isn't enough insulin to use glucose (sugar) for fuel, or when you haven't eaten for an extended period.

Why is it done?

This test is primarily used to: (1) Monitor ketone levels in people with diabetes, especially type 1 diabetes; (2) Help detect diabetic ketoacidosis (DKA), a potentially life-threatening complication of diabetes; (3) Check ketone levels during illness or pregnancy in diabetic patients; and (4) Sometimes used to assess compliance with or effectiveness of a ketogenic diet.

How is the test performed?

A urine sample is collected in a sterile container. The collection can be done at home or in a healthcare setting. For the most accurate results, it's best to collect the first morning urine sample, as it provides the most concentrated sample. The sample is then sent to a laboratory for analysis.

Understanding your results

Results are typically reported as either negative (normal) or positive. A negative result means no detectable ketones were found in your urine, which is the normal state. A positive result indicates the presence of ketones, which may require further evaluation by your healthcare provider.

Reference range

Negative or <1 mg/dL (<17.4 µmol/L)N/A

Specimen: urine

No fasting required. Collect random urine sample. Inform laboratory of any medications or supplements that may affect ketone metabolism.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings2

Frequently asked questions

Is fasting required before this test?
No specific fasting is required for a urine acetone test. However, test results may be affected by recent meals or fasting status, so inform your healthcare provider about your recent eating patterns.
Can I do this test at home?
Yes, there are home urine ketone test strips available over-the-counter. They work similarly to home glucose monitoring but measure ketone levels instead. Follow the package instructions carefully and discuss results with your healthcare provider.
What does a positive result mean?
A positive result means ketones were detected in your urine. The significance depends on your health status. For people with diabetes, this may indicate the need for immediate medical attention. For others, it may simply reflect a low-carbohydrate diet or overnight fasting. Always discuss results with your healthcare provider.
How often should I test for urine ketones?
For people with diabetes, testing frequency depends on your treatment plan. Common situations to test include: when blood glucose is consistently above 250 mg/dL, during illness, when experiencing symptoms of DKA (nausea, vomiting, abdominal pain), or as directed by your healthcare provider.
Are there medications that affect this test?
Certain medications may affect ketone test results, including sodium salicylate and vitamin C supplements. Inform your healthcare provider about all medications and supplements you are taking before the test.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy