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Acetonitrileurmcnc

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of acetonitrile in your urine to check for exposure to this toxic chemical.

Quick summary

{"Acetonitrile is a chemical used in industrial and laboratory settings","The test helps determine if you have been exposed to acetonitrile","Urine sample is collected and analyzed in a laboratory","Exposure can occur through inhalation, skin contact, or ingestion","Results help healthcare providers assess workplace safety and health risks"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
12987-4
Short code
AcnU
Synonyms
Acetonitrile Ur-mCnc
Category
chemistry
Sample
urine
Container
Clean, sterile, labeled urine container without preservatives
Units
N/A
Ref low
0
Ref high
0.5
Fasting
false
Population
adult
Sex
all
Age range
≥ 18 years
Method
Headspace Gas Chromatography-Mass Spectrometry (HS-GC-MS)
CPT
84600
SNOMED
39873001
Specimen volume
10-50 mL preferred
Stability
Refrigerate at 2-8°C if analyzed within 7 days; store at -20°C for longer periods; protect from light and heat
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
48–72 hours
Order
routine

What is this test?

The urine acetonitrile test measures how much acetonitrile, a toxic chemical compound, is present in your urine. Acetonitrile (also called methyl cyanide) is a colorless liquid used in many industrial applications, including manufacturing plastics, solvents, and pesticides. It is also used in some laboratory procedures and cosmetic products. Because acetonitrile can be harmful if inhaled, absorbed through the skin, or swallowed, this test helps determine if you have been exposed to dangerous levels of this chemical.

The test is typically performed when there is a concern about workplace exposure, such as in industrial settings, laboratories, or manufacturing facilities where acetonitrile is used. Healthcare providers may order this test as part of occupational health monitoring or if symptoms of acetonitrile exposure are present.

Reference range

Not detected; or < 0.5 mg/L (laboratory-specific cutoff)N/A

Specimen: urine

Collect clean-catch midstream urine sample; avoid contamination with external sources; inform laboratory of potential occupational exposure history; no fasting required

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Acetonitrile exposure primarily occurs in occupational settings where workers handle this chemical without adequate protection. Short-term exposure to high levels of acetonitrile can cause symptoms such as headache, dizziness, nausea, vomiting, difficulty breathing, and in severe cases, loss of consciousness or death. Long-term or repeated exposure may lead to more serious health effects including damage to the nervous system, liver, and kidneys.

This test is important for occupational health and safety monitoring. It helps employers and healthcare providers assess whether workplace safety measures are adequate and whether workers are being properly protected from harmful chemical exposure. The test may also be used in emergency situations when acute exposure is suspected, helping guide treatment decisions.

Results are interpreted based on the concentration of acetonitrile in the urine and may be compared to reference values or exposure limits established by occupational health organizations. Elevated levels indicate recent exposure, as acetonitrile and its metabolites are typically eliminated from the body within a few days.

Frequently asked questions

How is this test performed?
A urine sample is collected in a sterile container, typically in the morning or after a specific exposure period. The sample is then sent to a laboratory where it is analyzed using specialized equipment to measure the concentration of acetonitrile or its metabolites. No special preparation is usually required, though you should inform your healthcare provider about any medications or supplements you are taking.
Does the test require any special preparation?
Generally, no special preparation is needed. However, you should avoid consuming foods or beverages containing acetonitrile before the test if possible. Inform your healthcare provider about any medications, vitamins, or supplements you are taking, as these may affect the results. Follow any specific instructions provided by your healthcare provider or the testing facility.
What do the results mean?
Results are reported as the amount of acetonitrile or its metabolites in the urine, typically measured in mass per volume (such as milligrams per liter). Your healthcare provider will interpret the results based on the testing method used, your exposure history, and any symptoms you may have. Elevated levels suggest recent exposure to acetonitrile, while levels within the normal range suggest no significant exposure. Your provider will discuss what your specific results mean for your health.
Is the test safe?
The urine collection process is completely safe and non-invasive. The test itself poses no risks to the patient as it is performed on a urine sample that has already been collected. The main purpose is to protect your health by detecting harmful chemical exposure early.
How often should this test be done?
The frequency of testing depends on your work environment and potential for exposure. Workers in high-risk occupations may undergo regular monitoring as part of workplace safety programs. Your employer or occupational health department will determine the appropriate testing schedule based on exposure levels and safety regulations.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy