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Acetylsalicylateneutiggserplqlfc

Published: August 9, 2026Updated: August 17, 2026

This blood test detects IgG antibodies that develop against neutrophils after taking aspirin (acetylsalicylate).

Quick summary

A simple blood test that checks for antibodies triggered by aspirin Helps diagnose conditions related to aspirin sensitivity Sample is collected from a vein in your arm Results indicate whether aspirin has triggered an immune response

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
73058-0
Short code
ASA NEUT IgG
Synonyms
Acetylsalicylate (neut) IgG SerPl Ql FC
Category
chemistry
Sample
serum
Container
Serum separator tube (SST) or EDTA plasma tube
Units
N/A
Critical range
— – 50 N/A
Fasting
false
Population
adult
Sex
all
Age range
≥ 0 years
Method
flow-cytometry
CPT
86021
SNOMED
420079006
Specimen volume
1.0-2.0 mL serum or plasma
Stability
Room temperature: 24 hours; Refrigerated (2-8°C): 72 hours; Frozen (-20°C or below): 30 days. Avoid repeated freeze-thaw cycles.
Hemolysis max
50
Lipemia max
100
Icterus max
20
TAT
48–96 hours
Order
routine

What is this test, and why has my healthcare provider ordered it for me?

This test looks for IgG antibodies in your blood that target neutrophils (a type of white blood cell) after exposure to aspirin (acetylsalicylate). The test uses flow cytometry, a specialized laboratory technique that can detect and measure these specific antibodies.

How is the test performed, and what can I expect during the procedure?

A healthcare professional will draw a small blood sample from a vein in your arm. The sample is then sent to a laboratory where it is analyzed using flow cytometry to detect the presence of acetylsalicylate-induced neutrophil IgG antibodies.

Do I need to prepare for the test, such as fasting or adjusting my medications?

Your doctor will let you know if you need to stop taking aspirin or other medications before the test. It is important to inform your healthcare provider about all medications you are currently taking, including over-the-counter drugs and supplements.

Reference range

Negative - No significant acetylsalicylate-induced neutrophil IgG antibodies detected. Positive - Significant acetylsalicylate-induced neutrophil IgG antibodies present, suggesting aspirin hypersensitivity or drug-induced neutropenia.N/A

Specimen: serum

No special preparation required. Inform laboratory of current aspirin or other NSAID usage. Sample should be collected before discontinuing any aspirin therapy if testing is to demonstrate drug-induced effect.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test is primarily used to help diagnose conditions associated with aspirin-induced neutrophil antibody formation. It may be ordered when a patient shows symptoms suggesting an abnormal immune response to aspirin, such as unusual bruising, bleeding, or inflammatory conditions. The presence of these antibodies may indicate that the immune system is reacting to aspirin in an atypical way.

Frequently asked questions

Why do I need this test?
Your doctor may order this test if you are experiencing symptoms that might be related to an unusual reaction to aspirin, such as unexplained bruising, bleeding problems, or certain inflammatory conditions.
Is the test painful?
You may feel a brief pinch or mild discomfort when the blood sample is drawn, but the procedure is generally well-tolerated.
How long does it take to get results?
Results are typically available within a few days to a week, depending on the laboratory. Your healthcare provider will contact you with the results.
What do the results mean?
A positive result indicates the presence of acetylsalicylate-induced neutrophil IgG antibodies, suggesting an immune response to aspirin. A negative result means no antibodies were detected. Your doctor will interpret these results in the context of your overall health and symptoms.
Are there any risks with this test?
The risks are minimal and include slight bruising, bleeding, or infection at the needle site. These are rare and usually mild.
  1. 1
    LOINC Code ReferenceSource
  2. 2
    Flow Cytometry BasicsSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy