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Acute-phase reactant serum concentration (e.g., C-reactive protein, fibrinogen, or similar inflammatory marker)

Published: August 9, 2026Updated: August 16, 2026

This test measures levels of proteins in your blood that rise in response to inflammation, infection, or injury. It helps your healthcare provider assess whether your body is responding to illness or healing from a condition.

Quick summary

["This test helps track inflammation, infection, or healing progress in your body."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
68937-2
Short code
AChR Ab Ser IA-sCnc
Synonyms
AChR Ab Ser IA-sCnc
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is This Test Measuring?

Your blood contains many proteins that change in response to your body’s needs. Some, like **acute-phase reactants**, increase when you have an infection, injury, or inflammation. This test measures the concentration of one or more of these proteins, often including markers like C-reactive protein (CRP) or fibrinogen. These proteins don’t have a single, universally accepted name, so your results may refer to a group of related substances.

Why Might You Need This Test?

Healthcare providers use this test to monitor conditions such as infections (e.g., bacterial or viral), autoimmune diseases (e.g., rheumatoid arthritis), heart disease, or post-surgery healing. It may also be used to check for signs of inflammation after trauma or during certain treatments.

When Might You Get This Test?

You might receive this test if you have symptoms like fever, swelling, pain, or fatigue; if you’re recovering from surgery or an illness; or if your doctor suspects an underlying inflammatory condition. Some tests are done as part of routine check-ups or follow-up care.

What to Expect Before the Test

No special preparation is usually needed. You may be asked to fast for a few hours before the blood draw, but this depends on your healthcare provider’s instructions. On the day of the test, avoid smoking or consuming alcohol for at least 24 hours if directed.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Inflammatory marker screening

Frequently asked questions

How do acute-phase reactants help doctors?
Elevated levels of these proteins often indicate an active inflammatory process, infection, or tissue damage. For example, high CRP levels may signal infection or heart disease, while elevated fibrinogen could point to severe inflammation or trauma. However, results alone don’t diagnose a condition—they’re used alongside other tests and symptoms to guide treatment.
What do my results mean?
Your results will compare your protein levels to a reference range provided by your lab. If your levels are higher than expected, it may suggest inflammation, infection, or another underlying issue. If they’re lower, it could indicate certain immune system or liver problems. Always discuss your results with your healthcare provider.
Can I affect my test results?
Yes, factors like recent illness, stress, exercise, or certain medications (e.g., steroids) can influence your results. Avoiding these variables for a few days before testing can help ensure more accurate results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy