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Cortolone, Urine — Substance Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures cortolone, a corticosteroid-related substance, in urine. It may help evaluate adrenal steroid production or metabolism.

Quick summary

["Urine cortolone levels can provide information about adrenal steroid activity and metabolism."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
73871-6
Short code
A-cortolone Ur-sCnc
Synonyms
A-cortolone Ur-sCnc
Category
liver
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

This test measures the concentration of cortolone in urine. Cortolone is a substance formed during the metabolism of adrenal steroid hormones.

Why might I need this test?

A urine cortolone measurement may be used in a specialized evaluation of adrenal function, steroid metabolism, or the effects of corticosteroid medicines. It is usually interpreted with other hormone and metabolite tests.

How is the test performed?

Urine is collected and analyzed in a laboratory to determine the concentration of cortolone. The results may be expressed as an amount per unit of urine or adjusted using another measured value, depending on the ordered method.

How do I prepare for the test?

Follow the laboratory's urine-collection instructions, including whether a timed collection is required. Tell the care team about any corticosteroid medicines, other steroid medicines, supplements, or urinary problems that could affect the result.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Urine Cortolone

Frequently asked questions

What does a urine cortolone result tell me?
It indicates how much cortolone is present in the urine and may help assess adrenal steroid activity or metabolism. The result is most useful when interpreted with other tests and your health history.
Do I need to collect all of my urine for 24 hours?
That depends on the test order and the laboratory's instructions. Some measurements use a single urine sample, while others use a timed collection; follow the instructions provided before collection.
Can corticosteroid medicines affect the result?
Yes. Corticosteroid medicines and some other steroid medicines can change adrenal hormone levels and urinary metabolite measurements. Do not stop prescribed medicines without medical advice; instead, tell the care team what you are taking.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy