Complete Blood Count (CBC): What This Test Is and What Your Results Mean
A blood test that measures acylcarnitine levels to screen for metabolic disorders affecting how the body processes fats for energy.
{"Screens for fatty acid oxidation disorders and organic acidemias","Commonly used in newborn screening programs","Abnormal results may indicate a metabolic condition requiring treatment","The test helps doctors diagnose rare but serious inherited disorders","Early detection allows for proper management and prevention of complications"}
Key facts at a glance
- LOINC
- 31991-3
- Short code
- ACY
- Synonyms
- Acylcarnitine SerPl Ql
- Category
- chemistry
- Sample
- serum
- Container
- Serum separator tube (SST/gold top) or plain red top tube
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- ≥ 0 years
- Method
- Tandem Mass Spectrometry (MS/MS)
- CPT
- 82017
- SNOMED
- 313371009
- Specimen volume
- 1.0 mL minimum, 2.0 mL preferred for adequate testing
- Stability
- Room temperature: 24 hours; Refrigerated (2-8°C): 7 days; Frozen (-20°C or below): 30 days. Avoid repeated freeze-thaw cycles.
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 48–96 hours
- Order
- routine
A complete blood count, or CBC, is one of the most common blood tests. It measures the different cells in your blood, including red blood cells, white blood cells, and platelets. Your doctor may order it as part of a routine checkup or to help investigate symptoms such as fatigue, fever, weakness, or unusual bruising.
The acylcarnitine test measures the presence and levels of acylcarnitines in your blood. Acylcarnitines are substances produced when the body breaks down fatty acids for energy. This test helps detect metabolic disorders where the body cannot properly process fats, leading to a buildup of certain acylcarnitines in the blood.
The test is performed by drawing a small sample of blood, usually from a vein in your arm. A healthcare professional will clean the skin, wrap a band around your upper arm, and collect the blood into a small tube. The sample is then sent to a laboratory for analysis, and the entire process usually takes only a few minutes.
A healthcare professional will draw a small blood sample from a vein in your arm or, for newborns, from a heel stick. The blood is collected on a special filter paper and sent to a laboratory for analysis. No special preparation is typically required, though your doctor may ask about recent meals or medications.
A CBC can help detect a wide range of conditions, including anemia, infections, leukemia and other blood disorders, clotting problems, and signs of inflammation or immune system issues. It is also used to monitor chronic conditions and to track how well treatments, such as chemotherapy, are affecting your blood cells.
The acylcarnitine test primarily screens for inherited metabolic disorders, including: medium-chain acyl-CoA dehydrogenase (MCAD) deficiency, carnitine palmitoyltransferase (CPT) deficiencies, and various organic acidemias. These conditions affect how the body converts fat into energy and can cause serious health problems if not treated early.
Your results show whether your blood cell levels fall within normal ranges. Low red blood cells may suggest anemia, while a high white blood cell count can point to infection or inflammation, and abnormal platelet levels may affect clotting. Your doctor will interpret these values along with your symptoms and medical history to decide whether further testing or treatment is needed.
Normal results mean no abnormal levels of acylcarnitines were detected. Abnormal results may indicate a metabolic disorder, but further testing is usually needed to confirm a specific diagnosis. Your healthcare provider will interpret the results in the context of your symptoms, medical history, and other test results.
Reference range
Not Detected - The presence of abnormal acylcarnitine profiles may indicate inborn errors of metabolism such as fatty acid oxidation disorders, organic acidemias, or carnitine transport defects.N/A
No special preparation required. This test can be performed without fasting. Inform the laboratory of any medications, supplements, or recent parenteral nutrition as these may affect results.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
The acylcarnitine test is crucial for newborn screening programs, allowing early detection of potentially life-threatening metabolic disorders before symptoms appear. Early diagnosis enables prompt treatment with dietary modifications, supplementation, and avoidance of fasting, which can prevent serious complications such as developmental delays, organ damage, or sudden death. The test is also used for diagnostic testing in individuals of any age presenting with unexplained symptoms like recurrent vomiting, lethargy, or muscle weakness.
This test helps differentiate between various metabolic disorders based on the specific pattern of acylcarnitines detected. It guides treatment decisions and allows for family genetic counseling when an inherited disorder is confirmed.
Frequently asked questions
Why is this test done on newborns?
Does abnormal mean my baby definitely has a disorder?
Is fasting required before the test?
What happens if a disorder is diagnosed?
Sources
- 1
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- 3
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy