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Your Laboratory Test: What It Is, Why It Is Done, and What Your Results Mean

Published: August 9, 2026Updated: August 15, 2026

A blood test that measures the level of adenine, a building block of DNA and RNA, in your blood to evaluate kidney function and purine metabolism.

Quick summary

{"Measures adenine levels in blood serum or plasma","Helps assess kidney function and purine metabolism","Sample collected via routine blood draw","May be ordered to evaluate kidney disease or metabolic disorders","Results are interpreted along with other kidney function tests"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 15, 2026Editorial policy

Key facts at a glance

LOINC
75131-3
Short code
Adenine
Synonyms
Adenine SerPl-sCnc
Category
chemistry
Sample
serum
Container
Serum separator tube (SST) or plain red top tube
Units
N/A
Ref low
10
Ref high
50
Fasting
false
Population
adult
Sex
all
Age range
≥ 18 years
Method
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
CPT
82175 (Metabolic function, chromatographic assay) or 82679 (Chromatography, mass spectrometry)
SNOMED
314224001
Specimen volume
2-3 mL serum minimum
Stability
Serum: Room temperature 24 hours; Refrigerated (2-8°C) 72 hours; Frozen (-20°C or below) stable for several weeks. Protect from light.
Hemolysis max
50
Lipemia max
100
Icterus max
20
TAT
48–168 hours
Order
routine

This test is a laboratory analysis that gives your healthcare provider important information about your health by examining a sample, such as blood, urine, or another specimen, collected during your visit or at a lab.

The adenine blood test measures the amount of adenine in your serum or plasma. Adenine is a nucleobase—an essential building block of DNA and RNA—and is also a component of ATP (adenosine triphosphate), the main energy molecule in your cells. This test helps healthcare providers evaluate how well your kidneys are filtering waste products from your blood and assess disorders related to purine metabolism.

Your provider may order this test to check how well your body is functioning, look for signs of illness, confirm or rule out a diagnosis, screen for conditions before symptoms appear, or monitor an ongoing condition and how well your current treatment is working.

Your doctor may order an adenine test to: evaluate kidney function and detect kidney disease, monitor existing kidney conditions, assess purine metabolism disorders, investigate unexplained fatigue or metabolic problems, or evaluate certain genetic conditions affecting nucleotide processing.

The test is usually done by collecting a small sample, most often blood drawn from a vein in your arm, although some tests use urine, a swab, or another specimen; the collection itself typically takes only a few minutes, and the sample is then sent to a laboratory for analysis.

A healthcare professional will draw a small blood sample from a vein in your arm using a needle. The blood is collected into a tube and sent to a laboratory for analysis. You do not need to fast or prepare specially for this test, unless your doctor instructs otherwise.

Your results are compared with reference ranges that represent typical values for healthy people, and values outside these ranges do not always mean something is wrong; your provider will interpret the numbers together with your symptoms, medical history, and other test results before discussing what they mean for you.

Abnormal adenine levels may indicate kidney problems, as healthy kidneys help remove adenine from the blood. Elevated levels may suggest reduced kidney function or kidney disease. Your doctor will interpret your results alongside other kidney function tests (such as creatinine and BUN) to get a complete picture of your kidney health.

Reference range

Reference range not firmly established; consult laboratory. Typical reported range: 10-50 nmol/L for adults. Clinical interpretation should be based on specific clinical context and laboratory-specific reference values.N/A

Specimen: serum

No specific fasting required. Collect specimen using standard venipuncture technique. Avoid hemolysis. Inform laboratory of any medications that may affect purine metabolism.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

The adenine test is primarily used to assess renal (kidney) function. When kidneys are not filtering properly, adenine can accumulate in the blood. This test may also be useful in evaluating purine metabolism disorders, which can affect uric acid levels and potentially lead to conditions like gout. In research settings, adenine measurements may help study metabolic diseases and certain genetic disorders affecting nucleotide metabolism.

Frequently asked questions

Do I need to fast before this test?
Typically, no fasting is required for an adenine blood test. However, always follow your healthcare provider's specific instructions.
What does a high adenine level mean?
Elevated adenine levels may indicate reduced kidney function or kidney disease, as healthy kidneys filter and excrete adenine from the bloodstream. Your doctor will evaluate this result along with other tests to determine the cause.
Is this test painful?
You may feel a brief sting or pinch when the needle is inserted to draw blood. This is a routine blood draw similar to other common blood tests.
How long does it take to get results?
Results are typically available within a few days, but the exact time depends on the laboratory. Your healthcare provider will inform you when results are ready.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 15, 2026. · Read our editorial policy