Your Laboratory Test: What It Is, Why It Is Done, and What Your Results Mean
A blood test that measures the level of adenine, a building block of DNA and RNA, in your blood to evaluate kidney function and purine metabolism.
{"Measures adenine levels in blood serum or plasma","Helps assess kidney function and purine metabolism","Sample collected via routine blood draw","May be ordered to evaluate kidney disease or metabolic disorders","Results are interpreted along with other kidney function tests"}
Key facts at a glance
- LOINC
- 75131-3
- Short code
- Adenine
- Synonyms
- Adenine SerPl-sCnc
- Category
- chemistry
- Sample
- serum
- Container
- Serum separator tube (SST) or plain red top tube
- Units
- N/A
- Ref low
- 10
- Ref high
- 50
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- ≥ 18 years
- Method
- Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
- CPT
- 82175 (Metabolic function, chromatographic assay) or 82679 (Chromatography, mass spectrometry)
- SNOMED
- 314224001
- Specimen volume
- 2-3 mL serum minimum
- Stability
- Serum: Room temperature 24 hours; Refrigerated (2-8°C) 72 hours; Frozen (-20°C or below) stable for several weeks. Protect from light.
- Hemolysis max
- 50
- Lipemia max
- 100
- Icterus max
- 20
- TAT
- 48–168 hours
- Order
- routine
This test is a laboratory analysis that gives your healthcare provider important information about your health by examining a sample, such as blood, urine, or another specimen, collected during your visit or at a lab.
The adenine blood test measures the amount of adenine in your serum or plasma. Adenine is a nucleobase—an essential building block of DNA and RNA—and is also a component of ATP (adenosine triphosphate), the main energy molecule in your cells. This test helps healthcare providers evaluate how well your kidneys are filtering waste products from your blood and assess disorders related to purine metabolism.
Your provider may order this test to check how well your body is functioning, look for signs of illness, confirm or rule out a diagnosis, screen for conditions before symptoms appear, or monitor an ongoing condition and how well your current treatment is working.
Your doctor may order an adenine test to: evaluate kidney function and detect kidney disease, monitor existing kidney conditions, assess purine metabolism disorders, investigate unexplained fatigue or metabolic problems, or evaluate certain genetic conditions affecting nucleotide processing.
The test is usually done by collecting a small sample, most often blood drawn from a vein in your arm, although some tests use urine, a swab, or another specimen; the collection itself typically takes only a few minutes, and the sample is then sent to a laboratory for analysis.
A healthcare professional will draw a small blood sample from a vein in your arm using a needle. The blood is collected into a tube and sent to a laboratory for analysis. You do not need to fast or prepare specially for this test, unless your doctor instructs otherwise.
Your results are compared with reference ranges that represent typical values for healthy people, and values outside these ranges do not always mean something is wrong; your provider will interpret the numbers together with your symptoms, medical history, and other test results before discussing what they mean for you.
Abnormal adenine levels may indicate kidney problems, as healthy kidneys help remove adenine from the blood. Elevated levels may suggest reduced kidney function or kidney disease. Your doctor will interpret your results alongside other kidney function tests (such as creatinine and BUN) to get a complete picture of your kidney health.
Reference range
Reference range not firmly established; consult laboratory. Typical reported range: 10-50 nmol/L for adults. Clinical interpretation should be based on specific clinical context and laboratory-specific reference values.N/A
No specific fasting required. Collect specimen using standard venipuncture technique. Avoid hemolysis. Inform laboratory of any medications that may affect purine metabolism.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
The adenine test is primarily used to assess renal (kidney) function. When kidneys are not filtering properly, adenine can accumulate in the blood. This test may also be useful in evaluating purine metabolism disorders, which can affect uric acid levels and potentially lead to conditions like gout. In research settings, adenine measurements may help study metabolic diseases and certain genetic disorders affecting nucleotide metabolism.
Frequently asked questions
Do I need to fast before this test?
What does a high adenine level mean?
Is this test painful?
How long does it take to get results?
Sources
- 1
- 2
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 15, 2026. · Read our editorial policy