Understanding Your Laboratory Test: Sample Collection and What the Results Mean
A laboratory test that examines tissue samples under a microscope to identify and characterize adenomas (benign tumors).
{"Adenomas are non-cancerous growths that can develop in various organs","Histology examines tissue structure to determine if growths are benign or malignant","This test helps doctors understand the nature of detected tumors","Results guide treatment decisions and follow-up care","The test is performed on tissue obtained through biopsy or surgery"}
Key facts at a glance
- LOINC
- 67177-6
- Short code
- ADH
- Synonyms
- Adenoma histology PhenX
- Category
- chemistry
- Sample
- serum
- Container
- Tissue container with formalin (10% neutral buffered formalin) or fresh transport container
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- ≥ 18 years
- Method
- phenx
- CPT
- 88305
- SNOMED
- 400550006
- Specimen volume
- Tissue specimen of adequate size for processing (typically >2mm)
- Stability
- Formalin-fixed specimens: room temperature, stable for weeks to months. Fresh tissue: process within 1-2 hours
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 48–72 hours
- Order
- routine
This laboratory test gives your healthcare provider important information about your health by measuring substances in your body. It can be used to screen for illness, confirm or rule out a diagnosis, monitor an ongoing condition, or check how well a treatment is working. Your provider will explain why this test was ordered for you and what specific findings they are looking for.
The adenoma histology test is a laboratory examination that analyzes tissue samples under a microscope. Adenomas are benign (non-cancerous) tumors that can develop in various organs, including the colon, thyroid, pituitary gland, and adrenal glands. This test helps pathologists determine whether a growth is an adenoma or if it has features that require further investigation.
The way your sample is collected depends on the type of test your provider ordered. Most often, a trained technician draws a small amount of blood from a vein in your arm with a thin needle, a process that usually takes only a few minutes. Some tests instead require a urine sample, a throat or nasal swab, or a saliva sample. You may receive special instructions, such as fasting beforehand, so follow them carefully and tell the staff about any medications you take.
Unlike blood tests that use serum, adenoma histology requires a tissue sample. This tissue is obtained through procedures such as colonoscopy with polyp removal (polypectomy), surgical biopsy, or fine-needle aspiration. The collected tissue is then preserved and sent to a laboratory where a pathologist examines it under a microscope.
Your results are compared with established reference ranges to show whether your values fall within the expected range. A result within the normal range generally suggests no problem in the area being tested, while a value that is too high or too low may point to a condition that needs further evaluation. Keep in mind that factors such as age, medications, and recent meals can affect results, and a single abnormal value does not automatically mean you are ill. Always review your results with your healthcare provider, who can interpret them in the context of your symptoms and medical history and decide whether additional testing or treatment is needed.
The histology results provide important information about the tissue, including: whether the growth is benign (adenoma) or malignant (cancer), the specific type of adenoma, cell characteristics and growth patterns, and whether complete removal was achieved. Your doctor will explain these findings and what they mean for your specific situation.
Reference range
No adenoma present: Negative for adenomatous changes. Adenoma present: Classification by histologic type (tubular, tubulovillous, villous), grade (low-grade, high-grade dysplasia), and focal featuresN/A
No specific preparation required. Ensure proper identification and labeling of tissue specimen. Provide relevant clinical history including lesion location, size, and prior procedures
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Adenoma histology testing is crucial for distinguishing benign tumors from malignant cancers. While adenomas themselves are not cancerous, some types may have potential to become cancerous over time (malignant transformation). This test helps identify high-risk adenomas that may require more frequent monitoring or additional treatment. In colorectal cancer screening, detecting and removing adenomatous polyps through colonoscopy is a key prevention strategy.
Frequently asked questions
Is an adenoma the same as cancer?
How long does it take to get results?
Do I need to do anything special to prepare?
What happens after adenoma is found?
Sources
- 1
- 2
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy