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Adiponectinserplmcnc

Published: August 9, 2026Updated: August 15, 2026

A blood test that measures adiponectin levels to assess metabolic health, insulin sensitivity, and cardiovascular risk.

Quick summary

{"Adiponectin is a hormone produced by fat cells that helps regulate glucose and fatty acid breakdown","Low adiponectin levels are associated with obesity, type 2 diabetes, and heart disease","This test helps doctors evaluate metabolic health and cardiovascular risk","Blood is drawn from a vein in your arm","Results are interpreted along with other health markers"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 15, 2026Editorial policy

Key facts at a glance

LOINC
47828-9
Short code
ADPN
Synonyms
Adiponectin SerPl-mCnc
Category
chemistry
Sample
serum
Container
Serum separator tube (SST) or plain red top tube
Units
N/A
Ref low
2
Ref high
28
Fasting
false
Population
adult
Sex
all
Age range
18–100 years
Method
Enzyme-Linked Immunosorbent Assay (ELISA)
CPT
83520
SNOMED
413544009
Specimen volume
1.0-2.0 mL of serum
Stability
Room temperature: 24 hours; Refrigerated (2-8°C): 7 days; Frozen (-20°C or below): 3 months
Hemolysis max
50
Lipemia max
100
Icterus max
20
TAT
24–72 hours
Order
routine

What is this test?

The adiponectin test measures the amount of adiponectin in your blood. Adiponectin is a protein hormone secreted by fat cells (adipocytes) that plays a crucial role in regulating glucose levels and fatty acid breakdown. Unlike other hormones from fat tissue, higher levels of adiponectin are actually associated with better metabolic health.

Why do I need this test?

Your doctor may order this test to: evaluate your insulin sensitivity and risk for type 2 diabetes; assess your risk for cardiovascular disease; monitor metabolic conditions; understand unexplained weight changes; or check for metabolic syndrome. It provides valuable information about how your body processes energy.

How is the test performed?

A healthcare professional will draw a small blood sample from a vein in your arm using a needle. The sample is then sent to a laboratory for analysis. The procedure is quick and similar to other routine blood tests.

How should I prepare?

You may need to fast (not eat or drink anything except water) for 8-12 hours before the test. Follow your doctor's instructions carefully. Inform your doctor about any medications, supplements, or health conditions, as these may affect the results.

What do the results mean?

Adiponectin levels are typically measured in micrograms per milliliter (μg/mL) or milligrams per liter (mg/L). Generally, higher levels indicate better metabolic health and lower cardiovascular risk, while lower levels suggest higher risk for metabolic disorders. Your doctor will interpret your results alongside other health information.

Reference range

Male: 2.0-19.0 μg/mL; Female: 4.0-28.0 μg/mL (reference ranges may vary by laboratory and assay method)N/A

Specimen: serum

No special preparation required. Fasting is not mandatory but may be preferred. Avoid lipemic specimens as they may interfere with the assay.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Frequently asked questions

Does the test hurt?
You may feel a brief sting or pinch when the needle is inserted into your arm. This is typically well-tolerated, and the discomfort usually subsides quickly.
Are there any risks?
The risks are minimal and include minor bruising, bleeding, or infection at the puncture site. These are rare and usually resolve quickly.
How long does it take to get results?
Results are typically available within a few days to a week, depending on the laboratory. Your healthcare provider will contact you with the results.
Can exercise affect adiponectin levels?
Yes, regular exercise has been shown to increase adiponectin levels, which is one reason why physical activity is beneficial for metabolic health.
Will my insurance cover this test?
Coverage varies depending on your insurance plan and the medical reason for the test. Check with your insurance provider to confirm coverage.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 15, 2026. · Read our editorial policy