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What is this test?

The Aedes mosquito triggered histamine release test is a laboratory test that measures the amount of histamine released by your blood cells when exposed to allergens from Aedes mosquitoes (such as Aedes aegypti and Aedes albopictus). These mosquitoes are known carriers of diseases like dengue fever, Zika virus, and chikungunya. The test helps determine if you have an allergic reaction to mosquito bites.

How is the test performed?

A healthcare professional will draw a small sample of blood from a vein in your arm. The blood sample is then sent to a laboratory where it is mixed with Aedes mosquito allergens. If you are allergic, your blood cells (basophils) will release histamine in response. The laboratory measures the histamine concentration in the sample.

What do the results mean?

Results are typically reported as positive or negative. A positive result indicates that your immune system has developed specific antibodies (IgE) to Aedes mosquito allergens, suggesting you may experience allergic reactions to mosquito bites. These reactions can range from mild skin irritation (redness, itching, swelling) to severe local or systemic reactions in sensitive individuals.

Are there any risks?

The risks associated with this test are minimal and similar to routine blood tests. You may experience slight pain, bruising, or bleeding at the puncture site. In rare cases, fainting or infection may occur.