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Aspergillus fumigatus Antigen, Tissue — Qualitative Stain

Published: August 9, 2026Updated: August 16, 2026

A qualitative stain of a tissue sample looks for Aspergillus fumigatus antigen and may help support an Aspergillus infection diagnosis.

Quick summary

["A positive result can support the presence of Aspergillus in tissue, but results must be interpreted with the biopsy findings and clinical situation."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
10481-0
Short code
A-FSH Ag Tiss Ql ImStn
Synonyms
A-FSH Ag Tiss Ql ImStn
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
3.5
Ref high
12.5
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
immune-stain
CPT
83001
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This test examines a tissue specimen, usually from a biopsy, for antigens from the fungus Aspergillus fumigatus. It uses a qualitative laboratory stain to look for evidence of the fungus in the tissue.

Why might I need this test?

This test may be ordered when a biopsy or other clinical findings suggest an invasive fungal infection. It can help pathologists determine whether Aspergillus is present in affected tissue.

How is the test performed?

A laboratory specialist applies a special staining method to the tissue and examines it for a characteristic reaction. The result is generally reported as positive or negative for detectable Aspergillus antigen.

How do I prepare for the test?

No special preparation is usually required when the test is performed on a tissue sample that has already been collected. Follow the instructions provided by the healthcare team if a new biopsy or other specimen collection is planned.

Reference range

Follicular: 3.5-12.5 mIU/mLN/A

Specimen: serum

For females: inform if menstrual cycle status. For certain tests, timing within menstrual cycle may matter.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

A positive result may support Aspergillus infection when the stained tissue also shows compatible microscopic changes. A negative result does not completely exclude infection, especially if the amount of organisms is small or the sample is not representative. Results should be interpreted together with symptoms, imaging, culture or other laboratory findings, and the biopsy report.

Short name

Aspergillus antigen tissue stain

Frequently asked questions

Does a positive result prove that I have an Aspergillus infection?
No. It indicates that Aspergillus antigen was detected in the tested tissue and must be interpreted with the pathology findings and clinical evidence.
Can this test distinguish Aspergillus infection from colonization?
Not by itself. Tissue invasion, inflammation, imaging, and other clinical findings are needed to distinguish true infection from harmless colonization or contamination.
What happens if the tissue stain is negative?
A negative result means Aspergillus antigen was not detected by this method. The cause may be a true absence of infection, a low amount of fungus, or limitations of the sampled tissue.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy